and Answers
Which of the following side effects is common to the GnRH agonists, aromatase
inhibitors, and depot medroxyprogesterone? - Answer-Bone mineral density loss
What characteristic would preclude use of combined oral contraceptive pills to treat
endometriosis pain in a woman over age 35 due to increased risk of serious side
effects? - Answer-Tobacco use
Which of the following is a proposed theory for why endometrial tissue is found outside
the uterus in women with endometriosis? - Answer-Differentiation of stem cells from
bone marrow into endometrial-like tissues and retrograde flow of menstrual tissue
through the fallopian tubes
Which of the following medical therapies is considered a drug treatment of first choice
for endometriosis? - Answer-Depot medroxyprogesterone (subcutaneous)
KS is a 15-year-old female who presents to her family practitioner for followup after
presenting with severe menstrual pain 6 months prior. At that time, she was prescribed
a low-dose combined oral contraceptive pill continuously. Today, KS reports that her
pain has not improved. Based on this information, which of the following options is most
appropriate at this time? - Answer-Refer for laparoscopic evaluation.
TJ is a 65-year-old female who has suffered from endometriosis for most of her life. Five
years ago, she underwent hysterectomy with preservation of her ovaries. Prior to that
surgery, she had not had a menstrual cycle in 8 months time. Today, TJ again presents
with pelvic pain that is assessed to be due to relapsing endometriosis. Her PMH is also
positive for hypertension, hyperthyroidism, and osteoporosis. Her medications include
lisinopril 10 mg orally daily, amlodipine 5 mg orally daily, levothyroxine 75 mcg orally
daily, alendronate 70 mg orally weekly, and calcium/vitamin D supplementation. Which
of the following therapies is most reasonable to recommend at this time?. - Answer-
Anastrozole
CK is a 50-year-old female who has suffered from endometriosis since age 16. Over the
years, she has experienced both pain and infertility, and she and her husband selected
to adopt two children 10 years ago. Her last surgical treatment was 4 years ago, and
she presents again today with moderate-to-severe pain. What are the most appropriate
treatment goals for CK based on these data? - Answer-Preserve ovarian function. and
relieve pain
A 22-year-old female with endometriosis prefers to try a "natural and alternative"
approach to treating her pain before proceeding with traditional medical therapies.