NUR 354 Pharmacology II EXAM 3 latest 2023 |2024 C omplete QUESTION AND ANSWER Arizona college What class are statins? HMG -CoA reductase inhibitors What do statins do? Treat high cholesterol and prevent cardiovascular disease Risk factors for cardiovascular disease: Hypertension, diabetes, smoking Adverse effects of statins? Rhabdomyolysis What is rhabdomyolysis? The breakdown of muscle fibers Signs and symptoms of rhabdomyolysis? Sever muscle pain, weakness, and dark urine Before taking statins what should be checked? Lipid, AST, and ALT How to determine if statins are effective? By checking lipid, AST and ALT prior to administration Can you take statins while pregnant? No What to assess prior to education? The ability to learn What medication is a fibrate? Gemfibrozil What are Fibrates (Gemfibrozil)? Cholesterol medications What should Fibrates (Gemfibrozil) be given with? Food to prevent heartburn What is a complication of Fibrates (Gemfibrozil)? Gallstones Signs and symptoms of gallstones? RUQ pain What do PCSK9 inhibitors do? They prohibit the pcsk9 protein, which decreases the number of LDL receptors in the liver, therefore more LDL is excreted from the body which decreases cholesterol An Selective Cholesterol Absorption Inhibitor: Ezetimibe Adverse effects of Ezetimibe (Selective Cholesterol Absorption Inhibitor): Nasopharyngitis, upper respiratory infections, and diarrhea
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