NURS 5315 UTA EXAM 2 | NURS 5315 UTA EXAM 2 QUESTIONS AND CORRECT ANSWERS 2024 UPDATE -Osis or -philia - ✔✔✔ ANSWER Elevated count of blood cells -penia - ✔✔✔ ANSWER Low count of blood cells 4th generation immunoassay - ✔✔✔ ANSWER "gold standard" can test 10 days post exposure can result negative, positive with HIV antibody, or positive without HIV antibody Acute Lymphocytic Leukemia (ALL) - ✔✔✔ ANSWER Marked by >30% lymphoblasts in blood or marrow Most common in children Survival rate decreases with age CM: fever, pallor, bleeding, fatigue, lymphadenopathy, infection, joint pain, splenomegaly, h epatomegaly, night sweats, weight loss, anemia, thrombocytopenia, petechiae, ecchymosis Acute Myelogenous Leukemia (AML) - ✔✔✔ ANSWER Marked by proliferation of immature myeloid cells, decreased apoptosis, and lack of cellular differentiation Most common i n adults Remission is inversely related to age CM: fever, pallor, bleeding, fatigue, lymphadenopathy, infection, joint pain, splenomegaly, hepatomegaly, night sweats, weight loss, anemia, thrombocytopenia, petechiae, ecchymosis Alloimmunity and example of hypersensitivity - ✔✔✔ ANSWER When an individuals immune system reacts against antigens on the tissues of other members of the same species Blood transfusions - causes clumping and lysis of RBC - fever, nausea, chills, low back pain, dark urine, hives, itchi ng, SOB Rh incompatibility - hemolytic disease of newborn with jaundice, give Rhogam within 72 hours of birth (Rh - mother with Rh+ child) Antiretroviral medications - ✔✔✔ ANSWER Used to impede viral replication of HIV virus, come in 6 classes 1. Nucleoside reverse transcriptase inhibitors 2. Non -nucleoside reverse transcriptase inhibitors 3. Protease inhibitors 4. CCR5 inhibitors - inhibits binding to CCR3 5. Fusion inhibitor - inhibits fusion between HIV and cell membrane 6. Integrate inhibitor - inhibits viral integrate enzyme Arachidonic pathway purpose - ✔✔✔ ANSWER Synthesis of prostaglandins ASA - ✔✔✔ ANSWER Blocks COX1 and COX2, also inhibits Thromboxane A2 and prostaglandins Atopic disorders - ✔✔✔ ANSWER Genetic Type 1 hypersensitivity, asth ma, hay fever, eczema, urticaria Autoimmunity and example of hypersensitivity - ✔✔✔ ANSWER A breakdown of tolerance in which the bodies immune system begins to recognize self -antigens as foreign. Graves Disease - autoantibodies form against thyroid cells - bind to thyroid cells and mimic action of TSH, increases secretion of thyroxine Myasthenia Gravis - autoantibodies against acetylcholine bind to the post synaptic receptors and inhibit synaptic transmission of acetylcholine. Leads to muscle weakness and par alysis (mind to ground) Guillain -Barre' syndrome - antibodies bind with myelin sheath of the peripheral nervous system, triggering the immune response. Causes demyelination of the peripheral nerves and a rapidly progressive, ascending paralysis (ground to b rain)