BCH 2333 section 4 Questions with Correct Answers

BCH 2333 section 4 What makes about the anatomy of a virus? - Answer- Protein coat: Protect nuclear passage help infect passage Nucleic acid DNA or RNA Sheath and tail fibers in bacteriophage Membrane envelope in influenza They need a host Virion - Answer- Entire infectious particle Baltimore classification - Answer- a classification scheme that groups viruses into seven classes according to how the mRNA is produced during the replicative cycle of the virus. Viruses have many ways to guarantee protein production (morphology, size, shape, way of reproduction to organize) Lytic cycle - Answer- a viral reproductive cycle in which copies of a virus are made within a host cell, which then bursts open, releasing new viruses 1. attachment and penetration of the bacteriophage injecting genetic material into the cell 2. Circulation of phage DNA 3. Biosynthesis and assembly using cell machinery to make copies to assemble virus particles 4. Release (lysis) of virus cells causing cell death Lysogenic cycle - Answer- a viral reproductive cycle in which the viral DNA is added to the host cell's DNA and is copied along with the host cell's DNA 1. Attachment and penetration of bacteriophage 2. Integration of virus DNA into cell DNA. Stays like this for a random amount of time 4. Excision. Virus DNA exits cell DNA 5. enters lytic cycle by circulating, biosynthesis and assembly and lysis *Cycle depends on genome, host and environmental factors* What is SARS-CoV2 - Answer- -ssRNA virus -Family Coronaviridae -Affect humans and other mammals -Betacoronavirus: severe respiratory syndromes (This is why other coronas aren't as severe as they aren't part of this group) SARS-CoV2 genome - Answer- -Very simple -ORF1a ORF1b last part with spike taking up most -ORF1a: no structure proteins (accessory proteins) help other proteins to build and command aspects of virus structure when inside cells -ORF1b: Accessory help RNA conversion to DNA -Last part: Structure SARS-CoV2/COVID struture - Answer- -Big red crown like is spike glycoprotein (S) promotes attachment (Talk to cell to attach and penetrate) -Membrane protein (M) is orange tube in the coat to interact with structural protein, commands assemblage of viral particle -Envelope protein (E) is yellow tube, plays role in assemblage and interaction -Hemagglutinin-Esterase (HE) is blue tube, interacts with cell proteins in membrane facilitate viral entry in cell -Nucleoprotein (N) is light purple on inside, associated with genetic material to help RNA in cell -Viral RNA is the purple part on the inside