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Résumé glycolyse
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Résumé glycolyse UE1 PASS
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Profil métabolique d’organesCerveau MSS Coeur Foie
1. Glucose 1. AGL 1. AGL 1. AA
(120g/j)
⇒ CC/Gluc ⇒ CC ⇒ Gluc/AG
⇒ CC si jeûne ⇒ Glucose
Réserves: +++ ⇒ Lactate Glycolyse:
Pas de reserves: ultra Fournit précurseurs de
dépendant au glucose Production de lactate, ± de réserves biosynthèses:
alanine (néoglucogenèse) - Synth glycogène,
⇒ récup glucose NADPH, AG,
cholestérol, sels
biliaires.
Jeune vs post-prandiale
Jeune
Post-prandial
Physiologique Prolongé
- Néoglucogenèse - Proteolyse - Glucogénogenèse
- Lipolyse - Sécrétion de glucagon - Sécrétion d’insuline
⇒ Flux glucose maintenu par ⇒ Glucose utilisé But: éliminer le glucose
Alanine, Lactine ⇒ Acetyl CoA: AGL, CC
⇒ AGL, CC
Exercice musculaire
Bref et intense Long (endurance)
- Glycolyse, proteolyse, néoglucogenèse - β-oxydation des lipides
- Cycle de Cori (glycolyse + néoglucogenèse) - Lipolyse
- Cycle du lactate (métabolisme anaerobie)
↑ Intensité = ↑ oxydation glucides = ↑ oxidations lipides
ATP ↓: glycolyse ATP ↑: néoglucogenèse
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