SBB Human Blood Groups Exam Questions with Correct Answers | Latest .

SBB Human Blood Groups Exam Questions with Correct Answers | Latest . How would Ulex europaeus react with O, A, A2, B, A2B, A1B RBCs? - O>A2>B>A2B>A1>A1B 2. How could you distinguish serologically A1, A2 and A3 - Dolichos biflorus can will react with A1 and not A2. A3 yields mixed field reactions with anti-A and anti-A,B 3. What is the correct order of type of RBCs to transfuse in an AB patient when AB RBCs are not available? Why? - A, B, O; the residual antiB in A RBCs is less immunogenic than the residual anti-A in B RBCs 4. What type of RBCs would you transfuse to a patient with anti-G - RBCs transfused must lack the D and C antigens 5. Can you detect a weak D using Gel Technology? - No, because there is no washing phase 6. Can an Rh positive father and Rh positive mother yield an Rh negative child - Yes, if both parents are heterozygous for the D gene. Inheritance is autosomal recessive 7. What type of RBCs in regards to Rh phenotype would you transfuse in a patient with anti-f - RBCs should be negative for the c and e antigens SBB Human Blood Groups | 159 QUESTIONS WITH COMPLETE Answers | Latest [Date] 2 8. How could you solve an ABO discrepancy where Anti-M was causing aberrant results in reverse grouping when the forward type is consistent with A blood group and reverse as O? - Treat A1 cells with ficin to denature the M antigen, repeat reverse grouping with ficin-treated A1 cells. 9. Why do you see an anti-N like specificity in dialysis patients? - Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis procedures. 10.A patient types as follows: anti-A=4+, Anti-B=1+, A1 Cells=2+, B cells=4+. The ABO discrepancy led to suspicion of a possible cold autoantibody based on patient histopry and diagnosis. RESt was used in an attept to adsorb the autoantobidy. The type was repeated with adsorbed plasma Anit-A=4+, Anti-B=0, A1 cells=0, B cells=0. What could be the cause of this discrepancy? - Anti-B was adsorbed out with RESt. 11.What enzyme may be useful in distinguishing anti-Ge2? - papain 12.The beta 1-3 linkage between galactose and N-acetylglucosamine is found in? - secretions 13.Represents Type II chain - Beta 1-4 linkage between galactose and N acetyl glucosamine 14.Represents decreasing concentrations of H antigen on RBCs - O>A2>B>A2B>A1>A1B [Date] 3 15.The ABO genes are located on what chromosome - Chromosome 9 16.Which glycosyltransferase is needed before A and B antigens are formed? - L-fucosyltransferase 17.Which reflects the A3 subgroup - mixed field reactions with AntiA and Anti-A,B. 18.Which fo the following reflects the A el subgroup? - Positive reactions with Anti-H 19.What clinical condition may yield positive reactions with Anti-A, negative with Anti-B, negative with A1 and B cells. - hypogammaglobulinemia 20.What differentiates a Bombay anti-H from an anti-H cold agglutinin? - reactivity at body temperature. 21.This antigen is associated with linear carbohydrate chains - i antigen 22.The following reactions are found on a 35-year old male. Anti-A=4+, AntiB=0, Anti-A,B=4+, A1 cells=3+, B cells=4+, O cells=3+. How could these results be explained? - Anti-M in plasma 23.Anti-IH would react best with which red blood cells? - O RBCs [Date] 4 24.The acquired B phenomenon is only found in what ABO group? - A blood group 25.A2 subgroup - Anti-A1 does not react. 1-8% of persons will produce Anti-A1 26.Anti-Lu3 is associated with - Recessive type Lu(a-b-) 27.The dominant Lu(a-b-) type is associated with what gene? - In(Lu) 28.What substance could be used to rule out anti-E in the presence of antiLub? - DTT 29.Which pair of Lu alleles go together - Lu8 and Lu14 30.Lu6 and Lu9 31.Au^a and Au^b 32.Persons who are group B are more common among which population? - Black/Asian 33.Red cells that lack glycophorin A, also lack - En^a antigens 34.Anti-ENKT reacts with which RBCs? - En^a FS [Date] 5 35.What is a lectin? - Seed extracts that agglutinate human cells with moderate specificity. 36.All of the following are representative of the Lewis antibodies - They can be neutralized by Lewis substance; They occur frequently in pregnant women; They re enhanced by enzymes 37.Why can anti-H sometimes be found in A2B persons? - The specific immunodominant sugar blocks the presence of H antigen. 38.Why is determination of Rh status crucial for obstetric patients - All Rh negative mother s are possible candidates for Rhogam 39.Red cells that phenotype as Le(a-b-) will convert to Le(a+b-) when incubated with plasma from an adult containing? - Le(a+) substance 40.What genotype does hh represent - Bombay