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NAPLEX Diabetes Questions with 100% Correct Answers

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NAPLEX Diabetes Questions with 100% Correct Answers A1C goal for DM less than 7% preprandial blood glucose goal for DM 80-130 mg/dL Peak postprandial glucose goal in DM <180 mg/dL Drugs that can lower glucose beta blockers, quinolones, linezolid, lorcaserin, pentamide *can...

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  • June 13, 2024
  • 13
  • 2023/2024
  • Exam (elaborations)
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NAPLEX Diabetes Questions with 100%
Correct Answers
A1C goal for DM
less than 7%


preprandial blood glucose goal for DM
80-130 mg/dL


Peak postprandial glucose goal in DM
<180 mg/dL


Drugs that can lower glucose
beta blockers, quinolones, linezolid, lorcaserin, pentamide

*can also raise


Drugs that can raise glucose
beta blockers, thiazides, Loops, immunosuppressants (tacrolimus, cyclosporine), ~~~niacin, PIs~~~,
quinolones, atypical antipsychotics, statins, systemic steroids


If A1C is above _______, may start with dual therapy
8.5%


If A1c is 10% or above consider starting
insulin


If initiating dual therapy and the patient has ASCVD, choose one of the following:
GLP1: liraglutided, semaglutide, exenatide
SGLT2: empagliflozin, canagliflozin


If initiating dual therapy and the patient has HF or CKD, choose one of the following:
empagliflozin or canagliflozin

if those are not tolerated then use GLP1 (lira-, sem-, or exana-)


If initiating dual therapy and the patient has no ASCVD, HF, or CKD consider (three things and their
meds):
1. minimize hypoglycemia: DPP-4, GLP1, SGLT2, or TZD
2. weight loss: GLP or SGLT2
3. cost: SU or TZD


Three drug combinations that are not recommended
insulin with SU or meglitindies


Combo injectable therapy

, basal insulin and either a GLP-1 or mealtime insulin


Drugs that lower hepatic glucose output
metformin


Drugs that raise or replace insulin secretion
insulin, sulfonylureas, meglitinides


Drugs that lower glucagon (which lowers glucose production)
GLP-1, DPP-4, pramlintide


Drugs that slow gastric emptying
GLP-1, pramlintide


Drugs that raise glucose excretion
SGLT 2 inhibitors


Drugs that increase insulin sensitivity
metformin, TZDs


metformin & glipizide
Metaglip


metformin & glyburide
Glucovance


metformin & pioglitazone
Actoplus Met, Actoplus Met XR


metformin/alogliptin
Kazano


metformin/linagliptin
Jentadueto


metformin/sitagliptin
Janumet, Janumet XR


metformin/saxagliptin
Kombiglyze XR


metformin/canagliflozin
Invokamet

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