Advanced Pharm Final Exam
1.Which of the following adverse effects are less likely in a beta 1 selective blocker?
A.Reflex orthostatic changes
B.Dysrhythmias
C.Decreased triglycerides and cholesterol
D.Impair recovery from hypoglycemic episode
Answer Impair recovery from hypo- glycemic episode
2.While taking an angiotensin II receptor blocker (ARB), patients need to avoid certain OTC drugs without first consulting the provider because? (Select all that apply)
A.Tylenol related to hepatic enzyme competition
B.Cimetidine is metabolized by the CYP 3A4 isoenzymes
C.NSAIDs reduce prostaglandin levels
D.Loratadine can cause toxicity of the ARB to occur
Answer Cimetidine is metabolized by the CYP 3A4 isoenzymes, NSAIDs reduce prostaglandin levels .Furosemide is added to a treatment regimen for heart failure that includes digoxin. Monitoring for this combination includes
A.Hemoglobin
B.Serum potassium
C.Blood urea nitrogen
D.Serum glucose
Answer Serum potassium
4.Your patient has just received a diagnosis of migraine headaches. After reviewing the patient's medical history, you note that the patient uses a beta 2 agonist, albuterol metered dose inhaler intermittently for asthma. Why would propranolol, a beta blocker, be an inappropriate drug for migraine prophylaxis in this patient?
A.It may induce cerebral hypotension and hypoperfusing, thus increasing the intensity of her headache
B.It may induce bronchoconstriction or spasm which may result in an asthma attack
C.It is not inappropriate; she may use it without problems
D.It my increase her blood pressure which may result in increased headaches- Answer It may induce bronchoconstriction or spasm which may result in an asthma attack
5.Angiotensin converting enzyme (ACE) inhibitors treat hypertension be- cause they
select all that apply
A.Reduce sodium and water retention
B.Decrease cardiac oxygen demand
C.Decrease vasoconstriction D.Increase vasodilation
Answer Reduce sodium and water retention, decrease vasocon- striction, and increase vasodilation
6.Because primary hypertension has no identifiable cause, treatment is based on interfering with the physiological mechanisms that regulate blood pres- sure. Thiazide diuretics treat hypertension because they
A.Decrease the production of aldosterone
B.Deplete body sodium and reduce fluid volume
C.Increase renin secretion
D.Decrease blood viscosity
Answer Deplete body sodium and reduce fluid volume
7.Adherence to beta blocker therapy may be affected by the medications?
A.Short half-lives requiring twice daily dosing
B.Tendency to elevate lipid levels
C.Tendency to cause hunger
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