Pharm Exam 3 | Asthma, COPD, Allergic Rhinitis study guide

Asthma Triggers - Environment, Respiratory Infection, Allergens, Emotions, Exercise, Drugs/Preservations, Occupational Stimuli, Other Goals for Therapy - Reduce Impairment: -prevent chronic and troublesome symptoms -prevent use of rescue meds (2days/week) -maintain (near) normal pulmonary function and normal activity Reduce Risk: -prevent hospitalizations -prevent loss of lung function -provide optimal pharmacotherapy with minimal or no adverse effects of therapy Beta 2 Receptor Agonists (Short Acting) - Indicated for acute bronchospasm (rescue inhaler) Prevention of exercise induced asthma Albuterol (SABA) - Beta 2 Agonist, Potency: 2 Generic Available $45/mo 10 min onset, 3-4 hr duration Inhaler + Nebulizer Most clinical evidence bronchial hyperresponsiveness Levalbuterol (SABA) - No Generic $60/mo 10 min onset, 3-4 hr duration Inhaler + Nebulizer Pirbuterol (SABA) - No generic $145/mo 30 min onset, 5 hr duration Inhaler Beta 2 Receptor Agonists (Long-Acting) - -Preferred adjunctive therapy in combination with inhaled corticosteroids -Black Box Warning: used alone increases risk of asthma related death; increased asthma-related deaths with salmeterol -Indicated for long term control of asthma LABA Combinations - Salmeterol + Fluticasone Formoterol + Budesonide Formoterol + Mometasone Salmeterol - Generic available $181/mo 2 hr onset, 12 hr duration Inhaled aerosol powder More clinical evidence