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Class notes PRML133 Urinalysis & Body Fluids $5.99   Add to cart

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Class notes PRML133 Urinalysis & Body Fluids

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My notes comprehensively cover urine examination, detailing color variations, odor characteristics, transparency indicators such as turbidity causes (both pathologic and non-pathologic), and specific gravity implications, ensuring a thorough understanding for clinical assessment and diagnosis.

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  • June 30, 2024
  • 2
  • 2023/2024
  • Class notes
  • Ms. tan
  • Physical examination of urine
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Available practice questions

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Some examples from this set of practice questions

1.

What is the normal range of urine colors?

Answer: Colorless to amber

2.

Pigment causing yellow urine.

Answer: Urochrome

3.

Orange-red/reddish brown urine is caused by?

Answer: Urobilin

4.

Substances causing amber or orange urine.

Answer: Bilirubin, drugs (acriflavine, phenazopyridine, nitrofurantoin, phenindione)

5.

Causes of blue or green urine.

Answer: Pseudomonas infection, drugs ( amitriptyline, methocarbamol, clorets, indican, methylene blue)

6.

What makes urine pink or red?

Answer: Blood, beets

7.

Normal urine color.

Answer: Aromatic

8.

What does a fruity urine odor indicate?

Answer: Diabetes

9.

What does ammoniacal urine odor cause?

Answer: UTI

10.

What does fishy urine odor cause?

Answer: Trimethylaminuria

PHYSICAL EXAMINATION
COLOR
Normal Varies from almost colorless; straw or light yellow (low SG, increased volume) to dark yellow, yellow-orange, or amber
Pigments in Urine a. Urochrome – product of endogenous metabolism; increases in urine at room temperature
b. Uroerythrin – pink pigment seen in refrigerated urine due to precipitation of amorphous urates
c. Urobilin – oxidation product of urobilinogen; imparts an orange-brown color to urine
Variations a. Colorless / pale yellow – recent fluid consumption, polyuria DI, DM, alcohol consumption
b. Dark-yellow – concentrated specimen
c. Orange-red / reddish brown – urobilin
d. Amber / orange – bilirubin, acriflavine, phenazopyridine, nitrofurantoin, phenindione
e. Yellow-green / yellow-brown – bilirubin-biliverdin
f. Blue / green – pseudomonas infection, amitriptyline, methocarbamol, clorets, indican, methylene blue
g. Pink / red – intact RBCs, hemoglobin, myoglobin, porphyrins, beets, menstrual contamination
h. Brown / black – methemoglobin, homogentisic acid, melanin, phenol derivative, argyrols, methyldopa, levodopa, metronidazole



ODOR
Normal Faint aromatic, due to volatile acids; becomes ammoniacal as the specimen stands
Variations a. Ammoniacal (freshly voided) – UTI, (Proteous and other urease-producing bacteria)
b. Mousy – PKU
c. Rancid – Tyrosinuria
d. Sweaty feet – Isovaleric academia
e. Maple syrup / caramel-like – MSUD
f. Rotting fish – Trimethyl aminuria
g. Sulfur odor – cysteine disorders
h. Fecaloid – recto-vesicular fistula
i. Fruity / sweet – diabetes ketoacidosis (acetone or diacetic acid)
j. Cabbage / hops – methionine malabsorption
k. Mercaptan – ingestion of asparagus, garlic and eggs
l. Bleach - contamination



TRANSPARENCY
Normal Clear – no visible particulates, transparent
Variations a. Hazy – few particles, print easily seen through urine
b. Cloudy – many particulates, print blurred through urine
c. Turbid – print cannot be seen through urine
d. Milky – may precipitate or be clotted



NUBECULA

Faint, whitish cloud formed from mucus, cells, bacteria, and alkaline salts in old urine.

Non-pathologic causes of Turbidity Pathologic Causes of Turbidity
Epithelial Cells Red blood cells – 500/mm3
Normal crystal White blood cells- 200/mm3
Bacteria (old urine) Bacteria, yeasts
Semen, prostatic fluid Non-squamous epithelial cells
Fecal contamination Abnormal crystals, casts
Mucus Lymph fluid/chyle
Radiographic contrast media Lipids
h. Vaginal creams, talcum powder Fecal matter

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