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Immunology Exam 1 Questions With Verified Answers

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Immunology Exam 1 Questions With Verified Answers primary lymphoid organs bone marrow and thymus secondary lymphoid organs lymph nodes, spleen, Peyer's patches Hematopoietic stem cells are multipotent stem cells NK cells secrete perforins and granzymes NK cells release this...

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  • June 30, 2024
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Immunology Exam 1 Questions With Verified
Answers
primary lymphoid organs
bone marrow and thymus


secondary lymphoid organs
lymph nodes, spleen, Peyer's patches


Hematopoietic stem cells are
multipotent stem cells


NK cells
secrete perforins and granzymes


NK cells release this for communication
cytokines


Innate immune cells
neutrophils, macrophages, DC cells, mast cells, eosinophils, basophils, NK cells


Adaptive immune cells
T cells and B cells


B cells and T cells contain which receptors
BCRs and TCRs respectively


Cytokines
Secreted by cells for communication


Chemokines
cytokine that helps movement, migration and enhancement of adaptive immunity


tumor necrosis factor
cytokine that promotes anti-tumor and inflammation


What is humoral immunity?
antibody-mediated immunity


What are the antibody isotypes
IgA, IgE, IgD, IgG, IgM


What are antibody idiotypes?
variable regions (Fab)

, What antibody isotype is found in mucosal immunity?
IgA


what antibody is most common
IgG


Which antibody is first released
IgM


What determine if BCRs are membrane bound or secreted as antibodies
mRNA splicing


PRRs are located on
innate immune cells


Toll-like receptors (TLRs)
plasma membrane PRRs for extracellular pathogens


NOD-like receptors (NLRs)
Cytoplasmic PRRs for intracellular pathogens


Endosomal TLRs
DNA/RNA pathogens


Neutrophils
phagocytes responsible for bacteria and some viruses


the most abundant WBC is
neutrophil


DC cells are
Phagocytes and antigen presenting cells


DC cells are located
in the blood and peripheral tissues


Macrophages
phagocytes located in tissues


Which cells are antigen presenting cells
B cells, macrophages, dendritic cells

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