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All of the following donors would be permanently deferred EXCEPT which one? - correct answer 38-year-old male who received rabies vaccine after a dog bite 3 months ago All of the following donors would be permanently deferred: - correct answer 75-year-old male who had acute hepatitis 20 years ago following surgery, 19-y/o first-time donor who received human growth hormone 12 years ago, and a 24-y/o donor with a history of a positive test for Hepatitis C from another blood center. What is the interval between blood donations? - correct answer 8 weeks The oral temperature of a donor must not exceed which value? - correct answer 37.5 degrees C What is the minimum acceptable hemoglobin for blood donors? - correct answer 12.5 g/dL for allogeneic donors What is the lowest acceptable hematocrit for allogeneic donors? - correct answer 38% What donor meets the requirement for age, pulse, weight, and blood pressure? - correct answer Age: 32, Pulse: 60, Weight (lb) 185, BP: 110/70 How long must a pregnant woman be deferred? - correct answer 6 weeks postpartum There is a 12-month deferment for each of the following donors: - correct answer Donor received a blood transfusion, donor received a tattoo and body piercing, donor had sex with a person with hepatitis. There is a 12-month deferment for each of the following donors EXCEPT: - correct answer Donor received the hepatitis B vaccine How long must a prospective donor with a history of malaria be deferred? - correct answer 3 years after cessation of treatment A lab tech who has a positive tuberculin skin test wants to donate blood. If he/she meets all the other criteria, how long is the deferral? - correct answer No deferral as long as there is no other abnormality All of the following are causes of permanent donor deferral: - correct answer Confirmed HIV positive, family history of Creutzfedt-Jakob disease, and intravenous drug user All of the following are causes of permanent donor deferral EXCEPT: - correct answer Donor received the hepatitis B vaccine Current testing on all donor blood must include testing for which of the following? - correct answer Serological test for syphilis Which one of the following tests is not required by AABB and is therefore optional during donor blood testing? - correct answer anti-HBc What is a commonly used screening method for the detection of HIV-1 antibodies? - correct answer Enzyme-linked immunosorbent assays (ELISA) Currently required viral hepatitis marker tests include all of the following: - correct answer Anti-HCV, Anti-HBc, and HBsAg Currently required viral hepatitis marker tests include all of the following EXCEPT: - correct answer anti-HAV When color coding is used for donor blood labels, what color is group A? - correct answer Yellow Which infectious agent is least likely to be transmitted by a blood infection? - correct answer HAV In the very early acute phase of hepatitis, which one of the following tests would be indicative of onset of a viremic state? - correct answer HBsAg During the "window period," what is the only marker of HBV infection? - correct answer Anti-HBc What is the minimum length of time that the patient's serum must remain positive for HBsAg before the individual is referred to as a chronic carrier? - correct answer 6 months Which viral agent causes the majority of cases of transfusion-associated hepatitis? - correct answer HCV All of the following are required viral marker testing for the human immunodeficiency virus EXCEPT which one? - correct answer HIV-1 p24 antigen Which virus can be deadly to immunocompromised patients or premature infants? - correct answer CMV All of the following organisms have been implicated in bacterial contamination of donor blood products EXCEPT which one? - correct answer Escherichia coli All of the following organisms have been implicated in bacterial contamination of donor blood products: - correct answer Y. enterocolitica, C. freundii, and Pseudomonas putida Which one of the following parasites has NOT been transmitted by blood transfusion? - correct answer Naegleria Which parasites have been transmitted by blood transfusion? - correct answer Babesia, Plasmodium, and Trypanosoma What is the acceptable temperature range for a blood bank refrigerator? - correct answer 1-6 degrees C According to FDA regulations, if blood is to be transported, then what temperature must be maintained during transportation? - correct answer 1-10 degrees C What is the expiration date of RBCs preserved with CPDA-1? - correct answer 35 days What is the expiration date of RBCs preserved with ADSOL? - correct answer 42 days What is the shelf life of cryoprecipitated antihemolytic factor when stored at -18 degrees C or lower? - correct answer 1 year What is the shelf life of FFP that is stored at -18 degrees C or lower? - correct answer 1 year What is the optimum temperature for thawing FFP? - correct answer 30-37 degrees C What is the shelf life of platelet concentrates? - correct answer 5 days at 20-24 degrees C with constant agitation If the hermetic seal on a unit of packed RBCs has been broken, how soon must the product be used if stored in the blood bank refrigerator? - correct answer 24 hours Which biochemical change does NOT occur in stored blood? - correct answer Plasma K+ decreases Which biochemical changes occur in stored blood? - correct answer Plasma pH decreases, plasma Na+ decreases, and 2,3-DPG decreases Which one of the following is NOT a labeling requirement of specimens for crossmatching? - correct answer Ordering physician The following are labeling requirements of specimens for crossmatching? - correct answer Collection date, patient's name, hospital number All of the following statements concerning autologous transfusions are true EXCEPT which one? - correct answer There are no donor blood requirements for them All of the following statements concerning autologous transfusions are true: - correct answer They prevent alloimmunization, they are the safest possible transfusions, and they eliminate the risk of transfusion-transmitted infections. In which autologous procedure is blood drawn and stored before the anticipated elective surgery? - correct answer Preoperative collection For autologous blood donations, blood should not be drawn from the donor-patient within how many hours before the anticipated operation or transfusion? - correct answer 72 hours Which statement concerning the criteria for presurgical autologous donations is true? - correct answer Donor hemoglobin must be at least 11.0 g/dL Which of the following pretransfusion tests must be determined for an autologous transfusion recipient? - correct answer ABO/Rh testing What procedure involves the withdrawal of blood to obtain plasma abd subsequent reinfusion of the RBCs into the donor? - correct answer Plasmapheresis Collection of plasma by pheresis more often than once every 8 weeks necessitates that which analyte(s) is(are) monitored at 4-month intervals? - correct answer Total protein After donating a unit of whole blood, how long must a donor wait before he/she is eligible for plateletpheresis? - correct answer 72 hours How long must a plasmapheresis donor wait before donating whole blood? - correct answer 48 hours What is the separation of WBCs by reversible filtration or centrifugation called? - correct answer Leukapheresis Different genes that occupy a specific locus of a chromosome are called: - correct answer Alleles Which description best describes an amorph? - correct answer Gene with no directly observable product What term is used to describe two identical alleles at a particular locus? - correct answer Homozygous Which term best describes most blood group genes? - correct answer Codominant Which term best describes the gene inheritance of most blood group systems? - correct answer Autosomal codominant Which one of the following stimulates the production of antibodies? - correct answer Antigen What term best describes antibodies that are produced after exposure to foreign antigens that are stimulated by transfusion or pregnancy? - correct answer Alloantibodies The initial response to a foreign antigen is known as the primary response. The primary response usually takes how long to occur? - correct answer 2-6 months What term is used to describe the secondary response to the same foreign antigen characterized by a rapid increase in antibody synthesis? - correct answer Anamnestic response Which immunoglobulin class is produced by transfusion or pregnancy? - correct answer IgG If a mother passes an antibody to her fetus through the placenta, what type of immunity does the fetus have? - correct answer Naturally acquired passive immunity All of the following statements concerning complement are true EXCEPT: - correct answer It shows dosage effect with homozygous cells. All of the following statements concerning complement are true: - correct answer It is a group of at least nine plasma proteins, it causes hemolysis of RBCs, and it is activated by both IgG and IgM Which blood group system was discovered first? - correct answer ABO Which gene codes for the enzyme L-fucosyltransferase? - correct answer H gene An individual inherited the following genes: Sese Hh AO. Which of the following soluble antigens would be detectable in the saliva? - correct answer A and H Which system is composed of antigens found primarily in the saliva and plasma? - correct answer Lewis Mixed-field reaction with anti-A reagent and a negative reaction with anti-A1 lectin are observed. These results are most consistent with which A subgroup? - correct answer A3 Which one of the following antibodies will NOT be detected in the serum of a Bombay genotype? - correct answer anti-Oh Naturally occurring antibodies are found in which blood group system? - correct answer ABO Immune antibodies are stimulated by all of the following EXCEPT which one? - correct answer Immune system reacting to the environment RBCs of which blood group react most strongly with anti-H? - correct answer O What is the frequency of Group A individuals in the US population? - correct answer 41% Which statement is true concerning group B individuals? - correct answer Anti-A in their serum What is the standard acceptable color for anti-A grouping serum? - correct answer Blue What is the color of the dye added to the commercially prepared anti-B blood grouping serum? - correct answer Yellow Which reagent is made from the seeds of the plant Dolichos biflorus - correct answer anti-A1 RBCs of which blood group will not be agglutinated by anti-A,B serum? - correct answer O Which statement is true concerning anti-A,B - correct answer It is used to confirm group O individuals Wha
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