Exam (elaborations)
COMSAE Drugs – Complete Study Guide
- Course
- Institution
COMSAE Drugs – Complete Study Guide
[Show more]
Content preview
COMSAE Drugs – Complete Study GuideWarfarin- Mechanism Correct Ans - Interferes w/ vitamin K dependent clotting factors (II, VII, IX, X, C, S)
Warfarin- Pathway, effect on PT/INR Correct Ans - Extrinsic factor, increased PT
Warfarin- Clinical Use Correct Ans - Chronic anticoagulation
Warfarin- Pregnancy Correct Ans - CI in pregnant women--crosses placenta
Warfarin- AE Correct Ans - Bleeding, tissue necrosis
Digoxin- MOA Correct Ans - Direct inhibition of Na/K ATPase --> indirect
inhibition of Na/Ca exchange
Increased Calcium concentration --> positive ionotropy.
Stimulates vagus nerve --> decrease HR
Digoxin- Clinical use Correct Ans - Heart failure (increase contractility)
atrial fibrillation (decrease conduction at AV node and depression of SA node)
Digoxin- AE Correct Ans - Hyperkalemia, blurry yellow vision, arrhythmias, AV block
Digoxin Toxicity- Treatment Correct Ans - Slowly normalize K+, cardiac pacer, anti-digoxin Fab fragments, Mg+
Beta Blockers- Mechanism Correct Ans - Decrease SA and AV nodal activity by decreasing cAMP/Ca2+
Decrease slope of phase 4
Beta Blockers- Use Correct Ans - SVT, ventricular rate control for a-fib and a-flutter
Beta Blockers- AE Correct Ans - Exacerbation of COPD/asthma
CV effects: bradycardia, AV block, HF
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Studyhall. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
72042 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now