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2024 ATI RN PHARMACOLOGY PROCTORED EXAM VERSION 1, 2, 3 & 4, WITH NGN QUESTIONS AND VERIFIED ANSWERS / A+ GRADE

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2024 ATI RN PHARMACOLOGY PROCTORED EXAM VERSION 1, 2, 3 & 4, WITH NGN QUESTIONS AND VERIFIED ANSWERS / A+ GRADE

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  • July 14, 2024
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  • 2023/2024
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  • ATI RN PHARMACOLOGY
  • ATI RN PHARMACOLOGY

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数字技术的发展
例如，通过大数据分
将为政府提供更
此外，数字时代对人类思
析，政府可以更精准
加高效的管理工
维方式和行为模式也产生
地了解社会动态和民
此外，数字时代对人
具和手段。智能
了深远的影响。信息技术
众需求，提升公共服
2024 ATI RN
类思维方式和行为模
城市的建设，将
的普及，使得人们的思维
务的质量和效率。然
式也产生了深远的影
提升城市管理的
方式更加开放、灵活。互
而，数字时代的社会
响。信息技术的普及
精细化和智能化
联网提供了丰富的学习资
治理也面临着信息安
PHARMACOLOGY
，使得人们的思维方
水平，提高公共
源和交流平台，激发了人
全、隐私保护等方面
式更加开放、灵活。
服务的质量和效
们的创新意识和创造力。
的问题。网络犯罪、
互联网提供了丰富的
率。同时，数字
同时，社交媒体的兴起，
数据泄露等事件频发
PROCTORED
学习资源和交流平台
技术的发展也将
使得人们的交流方式更加
，给社会安全带来了
，激发了人们的创新
推动社会治理模
多样化此外，数字时代对
新的威胁例如，通过
意识和创造力。同时
式的变革，促进
人类思维方式和行为模式
大数据分析，政府可
EXAM VERSION 1,
，社交媒体的兴起，
政府与民众之间
也产生了深远的影响。信
以更精准地了解社会
使得人们的交流方式
的互动和沟通
息技术的普及，使得人们
动态和民众需求，提
更加多样化此外，数
的思维方式更加开放、灵
升公共服务的质量和
2, 3 & 4, WITH NGN
字时代对人类思维方
活。互联网提供了丰富的
效率。然而，数字时
式和行为模式也产生
学习资源和交流平台，激
代的社会治理也面临
了深远的影响。信息
发了人们的创新意识和创
QUESTIONS AND
着信息安全、隐私保
技术的普及，使得人
造力。同时，社交媒体的
护等方面的问题。网
们的思维方式更加开
兴起，使得人们的交流方
络犯罪、数据泄露等
放、灵活。互联网提
VERIFIED
式更加多样化
事件频发，给社会安
供了丰富的学习资源
全带来了新的威胁例
和交流平台，激发了
如，通过大数据分析
人们的创新意识和创
ANSWERS / A+
，政府可以更精准地
造力。同时，社交媒
了解社会动态和民众
体的兴起，使得人们
需求，提升公共服务
的交流方式更加多样
GRADE
的质量和效率。然而
化
，数字时代的社会治
理也面临着信息安全
、隐私保护等方面的
问题。网络犯罪、数
据泄露等事件频发，
给社会安全带来了新
的威胁例如，通过大
数据分析，政府可以
更精准地了解社会动
态和民众需求，提升
公共服务的质量和效
COMPREHENSION QUESTIONS
率。然而，数字时代
的社会治理也面临着

,8
[I.1] Bioavailability of an agent is maximal when the drug has which of the
following qualities?
A. Highly lipid soluble
B. More than 100 Daltons in molecular weight
C. Highly bound to plasma proteins
D. Highly ionize

,[I.2] An agent is noted to have a very low calculated volume of distribution
(Vd). Which of the following is the best explanation?
数字技术的发展
A. The agent 例如，通过大数据分
is eliminated by the kidneys, and the patient has renal
将为政府提供更
此外，数字时代对人类思
析，政府可以更精准
insufficiency.
B. The agent 加高效的管理工
维方式和行为模式也产生
地了解社会动态和民
is extensively bound to plasma proteins.
此外，数字时代对人
具和手段。智能
C. The agent了深远的影响。信息技术
is extensively sequestered in tissue.
众需求，提升公共服
D. The agent 类思维方式和行为模
城市的建设，将
is eliminated by zero-order kinetics.
的普及，使得人们的思维
务的质量和效率。然
[I.3] 式也产生了深远的影
提升城市管理的
Which of the方式更加开放、灵活。互
following describes the first-pass effect?
而，数字时代的社会
响。信息技术的普及
精细化和智能化
联网提供了丰富的学习资
A. Inactivation治理也面临着信息安
of a drug as a result of the gastric acids.
B. Absorption ，使得人们的思维方
水平，提高公共
of a drug through the duodenum.
源和交流平台，激发了人
全、隐私保护等方面
C. Drug given式更加开放、灵活。
服务的质量和效
orally is metabolized by the liver before entering the
们的创新意识和创造力。
的问题。网络犯罪、
circulation.互联网提供了丰富的
率。同时，数字
同时，社交媒体的兴起，
数据泄露等事件频发
D. Drug given学习资源和交流平台
IV accumulates quickly in the central nervous system
技术的发展也将
(CNS). 使得人们的交流方式更加
，给社会安全带来了
，激发了人们的创新
推动社会治理模
[I.4] A laboratory 多样化此外，数字时代对
新的威胁例如，通过
experiment is being conducted in which a mammal is
意识和创造力。同时
式的变革，促进
injected with人类思维方式和行为模式
大数据分析，政府可
a noncompetitive antagonist to the histamine receptor.
，社交媒体的兴起，
政府与民众之间
Which of the也产生了深远的影响。信
following best describes this agent?
以更精准地了解社会
使得人们的交流方式
的互动和沟通
A. The drug息技术的普及，使得人们
动态和民众需求，提
binds to the histamine receptor and partially activates
更加多样化此外，数
it. 的思维方式更加开放、灵
升公共服务的质量和
字时代对人类思维方
B. The drug活。互联网提供了丰富的
binds to the histamine receptor but does not activate it.
效率。然而，数字时
式和行为模式也产生
C. The drug binds to the receptor, but not where histamine binds, and
prevents学习资源和交流平台，激
代的社会治理也面临
the receptor
了深远的影响。信息 from being activated.
D. The drug发了人们的创新意识和创
着信息安全、隐私保
irreversibly binds to the histamine receptor and renders it
技术的普及，使得人
造力。同时，社交媒体的
ineffective.护等方面的问题。网
们的思维方式更加开
[I.5] A 25-year-old兴起，使得人们的交流方
络犯罪、数据泄露等
medical student is given a prescription for asthma,
放、灵活。互联网提
式更加多样化
事件频发，给社会安
which the physician states has a very high therapeutic index. Which
供了丰富的学习资源
of the statements best characterizes the drug as it relates to the ther-
全带来了新的威胁例
apeutic index?和交流平台，激发了
如，通过大数据分析
A. The drug’s人们的创新意识和创
serum levels will likely need to be carefully monitored.
，政府可以更精准地
B. The drug is造力。同时，社交媒
likely to cross the blood-brain barrier.
C.
了解社会动态和民众
The drug is体的兴起，使得人们
likely to have extensive drug-drug interactions.
D. 需求，提升公共服务
The drug is的交流方式更加多样
unlikely to have any serious adverse effects.
的质量和效率。然而
[I.6] A drug M is injected IV into a laboratory subject. It is noted to have
化
，数字时代的社会治
high serum protein binding. Which of the following is most likely to be
increased as a 理也面临着信息安全
result?
A. 、隐私保护等方面的
Drug interaction
B. 问题。网络犯罪、数
Distribution of the drug to tissue sites
C. Renal excretion
据泄露等事件频发，
D. Liver metabolism
给社会安全带来了新
的威胁例如，通过大
数据分析，政府可以
更精准地了解社会动
态和民众需求，提升
公共服务的质量和效
率。然而，数字时代
的社会治理也面临着

, 10

[I.7] A bolus of drug K is given IV. The drug is noted to follow first-order
kinetics. Which of the following describes the elimination of drug K?
A. The rate of elimination of drug K is constant.
B. The rate of elimination of drug K is proportional to the patient’s
renal function.
C. The rate of elimination of drug K is proportional to its concentra-
tion in the patient’s plasma.
D. The rate of elimination of drug K is dependent on a nonlinear rela-
tionship to the plasma protein concentration.


Answers
[I.1] A. Transport across biologic membranes and thus bioavailability is
maximal with high lipid solubility.
[I.2] B. The volume of distribution is calculated by administering a known
dose of drug (mg) IV and then measuring an initial plasma concen-
tration (mg/L). The ratio of the mass of drug given (mg) divided by
the initial plasma concentration (mg/L) gives the Vd. A very low Vd
may indicate extensive protein binding (drug is sequestered in the
bloodstream), whereas a high Vd may indicate extensive tissue bind-
ing (drug is sequestered in the tissue).
[I.3] C. The first-pass effect refers to the process in which following oral
administration a drug is extensively metabolized as it initially passes
through the liver, before it enters the general circulation. Liver
enzymes may metabolize the agent to such an extent that the drug
cannot be administered orally.
[I.4] C. A noncompetitive antagonist binds to the receptor at a site other
than the agonist-binding site and renders it less effective by prevent-
ing agonist binding or preventing activation.
[I.5] D. An agent with a high therapeutic index means the toxic dose is
very much higher than the therapeutic dose, and it is less likely to
produce toxic effects at therapeutic levels.
[I.6] A. High protein binding means less drug to the tissue, the kidney, and
the liver. Drug interaction may occur if the agent binds to the same
protein site as other drugs, thus displacing drugs and increasing
serum levels.
[I.7] C. First-order kinetics means the rate of elimination of a drug is pro-
portional to the plasma concentration.

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