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2024 Pharmacology II Hesi Questions and Answers Pharm II
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Master Pharmacology II with our 2024 HESI exam guide. Get the latest questions and answers to excel in your Pharm II coursework and exams.
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2024 PHARMACOLOGY II HESIQUESTIONS AND ANSWERS
PHARM II
, lOMoARcPSD|14985576
HESI QUESTIONS (RED BOOK/EVOLVE)
A client with chronic gouty arthritis is talking allopurinol, 100 mg PO daily. Which laboratory
serum level should the nurse report to the health care provider to determine the therapeutic
outcome?
Rationale:
The primary therapeutic outcome associated with allopurinol therapy is reduced serum uric acid
levels with a lower frequency of acute gouty attacks, so option B should be reported to the health
care provider. Options A, C, and D are not related to the effectiveness of allopurinol.
A. Prothrombin time
B. Uric acid level
C. White blood cell count
D. Creatinine level
Following the administration of sublingual nitroglycerin, which assessment finding indicates that
the medication was effective?
Rationale:
Nitroglycerin reduces myocardial oxygen consumption, which decreases ischemia and reduces
chest pain. Options B, C, and D are not expected outcomes of sublingual nitroglycerin.
A. Decrease in level of chest pain
B. Clear bilateral breath sounds
C. Increase in blood pressure
D. Increase in urinary output
Prior to administering a scheduled dose of digoxin, the nurse reviews the client's current serum
digoxin level, which is 1.3 ng/dL. Which action should the nurse implement?
Rationale:
The client's digoxin level of 1.3 ng/dL is not above the upper range of its therapeutic index (toxic
level is >2.0 ng/dL), so the dose should be administered after the client's heart rate is evaluated.
Digibind is administered for toxic levels of digoxin, so option A is not indicated. Options B and
C are not necessary.
A. Administer Digibind to counteract the toxicity.
B. Withhold the drug and notify the health care provider
immediately.
C. Withhold the dose and notify the health care provider
during rounds that the dose was held.
D. Give the dose of digoxin if the client's heart rate is
within a safe range.
, lOMoARcPSD|14985576
Methenamine mandelate is prescribed for a client with a urinary tract infection and renal calculi.
Which finding indicates to the nurse that the medication is effective?
Rationale:
Mandelamine is prescribed to acidify the urine, decreasing the incidence of calcium phosphate
calculi and urinary tract infections. Option B is related to the administration of pyridine.
Mandelamine has no effect on option C or D.
A. The frequency of urinary tract infections decreases.
B. The urine changes color and pain is diminished.
C. The dipstick test changes from +1 to trace.
D. The daily urinary output increases by 10%.
A 4-year-old child is receiving chemotherapy for acute lymphocytic leukemia. Which laboratory
result should the nurse examine to assess the child's risk for infection?
Rationale:
During chemotherapy, granulocytes are significantly suppressed. Because neutrophils comprise
60% to 70% of the granulocyte count, these levels are the most useful laboratory results of the
options presented to determine the child's risk for infection. Options B, C, and D are not as
useful as option A in determining risk of infection.
A. Neutrophil count
B. Platelet count
C. Reticulocyte count
D. Lymphocyte count
When providing client teaching about the administration of methylphenidate (Ritalin) to a parent
of a child diagnosed with ADHD, which instruction should the nurse include in the teaching
plan?
Rationale:
Administering the medication at breakfast and after lunch provides the correct spacing of the
doses to maximize the child's attention span and helps prevent the appetite suppression
associated with the drug. Doses should be spaced at 6-hour intervals, not option A. Option B is
likely to increase insomnia. Option C disrupts the normal dosing schedule, resulting in
ineffective treatment. Doses should be discontinued only for brief intervals (with the health care
provider's approval) when the client's condition is being evaluated or if the client is being
weaned from the medication entirely.
A. The doses should be given exactly 12 hours apart to sustain
a therapeutic serum level.
B. Doses should be scheduled at midmorning and
midafternoon to achieve optimal benefit.
C. Give the medication only on school days and when the
child appears to be anxious.
D. Offer the child the medication with breakfast and after
the child eats lunch.
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A client is ordered 22 mg of gentamicin by IM injection. The drug is available in 20 mg/2 mL.
How many milliliters should be administered?
Rationale:
(22 mg/20 mg) × (x mL/2 mL) = 22x = 40
x = 2.2 mL
A. 1.8
B. 2.0
C. 2.4
D. 2.2
A chemotherapeutic regimen with doxorubicin HCl is being planned for a client recently
diagnosed with cancer. What diagnostic test results should the nurse review prior to initiating this
treatment?
Rationale:
Baseline cardiac function studies are required to monitor the irreversible cardiotoxic effects of
doxorubicin HCl. Option B assesses disturbances of acid-base balance. Option C is not affected
by this chemotherapeutic agent. Option D is used to detect pelvic abnormalities such as tumors
but is not specific for the administration of doxorubicin HCl.
A. Electrocardiogram (ECG)
B. Arterial blood gases (ABGs)
C. Serum cholesterol level
D. Pelvic ultrasound
A female client is receiving tamoxifen following surgery for breast cancer. She reports the onset
of hot flashes to the nurse. Which intervention should the nurse implement?
Rationale:
Tamoxifen is an estrogen receptor blocker used to treat breast carcinoma. Hot flashes are a
common side effect. If the hot flashes become bothersome, the client can be instructed in
measures to reduce the discomfort. Hot flashes are not an indication of option B, C, or D.
A. Instruct the client that hot flashes are a side effect that
often occurs with the use of this medication.
B. Encourage the client to verbalize her feelings and fears
about the recurrence of her breast cancer.
C. Help the client schedule an appointment for evaluation of
the need to increase the dose of medication.
D. Notify the health care provider that the client needs
immediate evaluation for medication toxicity.
Which response best supports the observations that the nurse identifies in a client who is
experiencing a placebo effect?
Rationale:
The placebo effect is a response in the client that is caused by the psychological impact of taking
an inert drug that has no biochemical properties. A placebo effect can be therapeutic, negative, or
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