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pharm exam 1 NUR 2060 (2

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pharm exam 1 NUR 2060 (2

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  • July 22, 2024
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  • 2023/2024
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pharm exam 1 NUR 2060
_________________ is more effective when used with dexamethasone (a steroid med) -
ANS-serotonin receptor antagonist

ADR's of weight loss drugs - ANS-decreases fat soluble vitamins and beta-carotene; may
decrease absorption of thyroid hormone replacement,

antibiotics to eradicate H. pylori - ANS--amoxicillin (Amoxil)
-bismuth (Pepto Bismil)
-metronidazole (Flagyl)

anticholinergic example - ANS-scopolamine (Transderm scop)

anticholinergic uses and effects - ANS-nausea, vomiting, motion sicknes
-effects: blurred vision, dry mouth, drowsiness, urinary retention, constipation

Antihistimine uses - ANS-motion sickness and vertigo symptoms of vertigo

bismuth subsalicylate - ANS--gastric cytoprotectant: possess topical mucosal effects
-antimicrobial effects: binds to bacterial toxins
-is an NSAID (risk for reyes syndrome in infants)

bismuth subsalicylate uses - ANS--H. pylori infection (adults and children)
-diarrhea (ages 12 and older)
-traveler's diarrhea propylaxis

butyrophenone use - ANS-antagonizes dopamine & alpha receptors

can a REMS drug be given to any patient? - ANS-no, only patients in certain healthcare
settings, e.g. hospitals or physician's offices.
-only dispensed to patients with specific documentation showing they're approved
-patients are subject to monitoring

cannabinoids: - ANS--bind to cannabinoid receptors
-are second line due to unpleasant temporal effects and dependence potential
-can be used to stimulate appetite

causes of acute diarrhea - ANS--infection (e. Coli and c. Dif)
-GI disease
-change in diet
-nervousness and anxiety

, -allergic rxn
-intoxication
-side effect of medication

causes of chronic diarrhea - ANS--related to disease or disorder
-malabsorption syndrome
-inflammatory bowel disease
-endocrine disorder

chloride channel activator action - ANS-promotes secretion of chloride into the bowel by
activating chloride channels and enhance motility and fluid secretion in small intestine
semisoft stool in 24 hours
potential teratogen

chloride channel activator example - ANS-lubiprostone (Amitiza)

does cardiac output increase or decrease with aging? - ANS-decreases
-decreased arterial elasticity

does every drug need REMS? - ANS-no

dopamine antagonist example - ANS-metoclopramide (Reglan)

dopamine antagonist uses - ANS-antagonizes dopamine, stimulates GI tract mobility (pro-kinetic
subclass)

during which weeks are fetuses most at risk for physical malformations? - ANS-weeks 3-8
-teratogen exposure during this period

during which weeks are fetuses most at risk for physiological malformations? - ANS-weeks
9-term

histamine H2 receptor antagonist examples - ANS--cimetidine (Tagamet)
-ranitidine (Zantac)
-famotidine (Pepcid)

IBS medications - ANS--dicyclomine (Bentyl)- decreases GI motility, antichollinergic, good for
cramps and abdominal pain
-alostetron (Lotronex)- only for women with severe diarrhea inducing IBS, REMS program used
with this
-lubiprostone (Amitiza)- chloride channel activator for constipating IBS

indications of chloride channel activator - ANS-chronic idiopathic constipation
constipating irritatable bowel syndrome

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