Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
PHARMACOLOGY
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
1. Which route of drug administration is the oldest and commonest?
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
a) Inhalation • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
b) Sublingual
• Respiratory infections (e.g., bronchiolitis, asthma)
c) Oral • Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
d) IntravenousCommon Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal
Answer: Oral ( “Oral ingestion is issues (e.g., and
the oldest gastroenteritis,
commonest constipation)
mode of drug
• Skin conditions (e.g., eczema, diaper rash)
administration.”)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
2. Which type • ofSkin conditions
drug (e.g., eczema,
administration is useddiaper rash) liquids and gases for systemic
for volatile
Common Pediatric Illnesses:
action?
• Respiratory infections (e.g., bronchiolitis, asthma)
a) Nasal • Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
b) Inhalation Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
c) Oral • Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
d) IntravenousCommon Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
Answer: Inhalation (“Volatile liquids
• Gastrointestinal issuesand gases
(e.g., are given by
gastroenteritis, inhalation for systemic
constipation)
action.”) • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
3. What is the• form
Skinof a drug used
conditions (e.g.,for the rectal
eczema, route?
diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
a) Tablets • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
b) Suppositories • Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
c) Inhalers • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
d) Patches
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal
Answer: Suppositories issues (e.g.,
(“Certain irritant andgastroenteritis, constipation)
unpleasant drugs can be put into rectum as
• Skin conditions (e.g., eczema, diaper rash)
suppositoriesCommon
or retention enema
Pediatric for systemic effect.”
Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
, Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
4. Why Common
might a drug be administered sublingually?
Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
a) To slow down •the Skin
drugconditions
absorption(e.g., eczema, diaper rash)
Common Pediatric Illnesses:
b) To avoid liver •metabolism
Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin
c) To cause irritation conditions
in the mouth (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
d) To prevent drug • degradation
Respiratory by digestive
infections juices
(e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
Answer: To avoid • liver
Skin metabolism ( “The
conditions (e.g., chief
eczema, advantage
diaper rash) is that liver is bypassed and
drugs with highCommon Pediatric
first pass Illnesses:can be absorbed directly into systemic circulation.”)
metabolism
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
5. Which route• involves
Respiratory infections
applying (e.g.,directly
a drug bronchiolitis,
to theasthma)
skin for slow and prolonged
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
absorption?
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
a) Intramuscular • Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
b) CutaneousCommon Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
c) Sublingual • Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
d) IntravenousCommon Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
Answer: Cutaneous (“Highly lipidissues
• Gastrointestinal soluble drugs
(e.g., can be applied
gastroenteritis, over the skin for slow and
constipation)
• Skin conditions (e.g., eczema, diaper rash)
prolonged absorption.”)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
6. What is a•major Skindisadvantage of the
conditions (e.g., oral route
eczema, diaperof administration?
rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
a) It requires sterile
• preparations
Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
b) It is painful • Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
c) It cannot be used for uncooperative/unconscious patients
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
d) It is suitable for emergencies
• Respiratory infections (e.g., bronchiolitis, asthma)
Answer: It cannot • be Gastrointestinal issues (e.g., gastroenteritis, constipation)
used for uncooperative/unconscious patients (“Cannot be used for
• Skin conditions (e.g., eczema, diaper rash)
uncooperative/unconscious/
Common Pediatric vomiting
Illnesses:patient.”)
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
, Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
7. If a patient is vomiting and requires medication, which route could be used for
Common Pediatric Illnesses:
administration?
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
a) Oral • Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
b) Rectal
• Skin conditions (e.g., eczema, diaper rash)
c) Intravenous Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
d) Sublingual • Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Answer: Rectal (“ThisPediatric
Common route canIllnesses:
also be used when the patient is having recurrent vomiting
• Respiratory infections (e.g., bronchiolitis, asthma)
or is unconscious.”)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory
8. Which method is used toinfections (e.g.,without
inject drugs bronchiolitis,
a needleasthma)
by projecting a high-velocity jet?
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
a) Pellet implantation
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
b) Dermojet • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
c) Sialistic implants
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
d) Intramuscular • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
Answer: Dermojet • (“In this method
Respiratory needle
infections (e.g.,isbronchiolitis,
not used; aasthma)
high velocity jet of drug solution is
projected from a• microfine orificeissues
Gastrointestinal using(e.g.,
a gun like implement.”)
gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
9. What could • be a reason to choose
Gastrointestinal issues a(e.g.,
transdermal therapeutic
gastroenteritis, system over oral tablets?
constipation)
• Skin conditions (e.g., eczema, diaper rash)
a) Lower costCommon Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
b) Non-invasive administration
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions
c) Slow and unpredictable (e.g., eczema, diaper rash)
drug release
Common Pediatric Illnesses:
• Respiratory
d) Causes more side effects infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skinadministration
Answer: Non-invasive conditions (e.g., (“Though
eczema, diapermorerash)
expensive, they provide smooth
Common Pediatric Illnesses:
plasma concentrations of the drug without fluctuations; minimize interindividual
• Respiratory infections (e.g., bronchiolitis, asthma)
variations (drug•is subjected to little
Gastrointestinal first
issues pass
(e.g., metabolism)
gastroenteritis, and side effects.”)
constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
, Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
10. Why is the• intravenous routeissues
Gastrointestinal considered the most risky?
(e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
a) It causes local •irritation
Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skinslowly
b) The drug is absorbed conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
c) Vital organs are• exposed
Respiratory infections
to high (e.g., bronchiolitis, asthma)
drug concentrations
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin
d) It requires special conditions (e.g., eczema, diaper rash)
preparation
Common Pediatric Illnesses:
• Respiratory
Answer: Vital organs are exposed to high
infections drug
(e.g., asthma)(“However, this is the most
concentrations
bronchiolitis,
• Gastrointestinal issues (e.g., gastroenteritis,
risky route—vital organs like heart, brain, etc. get exposed constipation)
to high concentrations of the
• Skin conditions (e.g., eczema, diaper rash)
drug.”) Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• would
11. Which route Skin conditions (e.g., eczema,
you recommend diaper rash) a highly irritant drug?
for administering
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
a) Subcutaneous • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
b) Intramuscular • Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
c) Oral • Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
d) Intravenous • Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
Answer: Intravenous• Skin ( “The intima
conditions of veins
(e.g., eczema, is diaper
insensitive
rash) and drug gets diluted with blood,
therefore, even highlyPediatric
Common irritant Illnesses:
drugs can be injected i.v.”)
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
12. What Common
is an advantage of the
Pediatric parenteral route over the oral route?
Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
a) Non-invasive and
Common painless
Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
b) Self-administration is easy
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
c) No need for sterility
Common Pediatric Illnesses:
• Respiratory
d) Bypasses digestive juices andinfections
liver (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
Answer: Bypasses • digestive juices(e.g.,
Skin conditions and eczema,
liver (“Thediaperlimitations
rash) of oral administration are
Common Pediatric Illnesses:
circumvented. Drug action is faster and surer (valuable in emergencies). Gastric irritation
• Respiratory infections (e.g., bronchiolitis, asthma)
and vomiting are • not provoked. Parenteral
Gastrointestinal issues (e.g.,routes can be employed
gastroenteritis, constipation)even in unconscious,
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)
• Skin conditions (e.g., eczema, diaper rash)
Common Pediatric Illnesses:
• Respiratory infections (e.g., bronchiolitis, asthma)
• Gastrointestinal issues (e.g., gastroenteritis, constipation)