Exam 1 Review AMR Questions and Answers (Graded A)
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Course
AMR
Institution
AMR
Exam 1 Review AMR Questions and Answers (Graded A)Exam 1 Review AMR Questions and Answers (Graded A)Exam 1 Review AMR Questions and Answers (Graded A)Exam 1 Review AMR Questions and Answers (Graded A)
B-lactams - ANSWER-Cell wall synthesis
Aminoglycosides - ANSWER-Binding of aminoglycosides to ...
Exam 1 Review AMR Questions and Answers (Graded A)
B-lactams - ANSWER-Cell wall synthesis
Aminoglycosides - ANSWER-Binding of aminoglycosides to 30S ribosomal subunit leads to inhibition of tRNA translocation from A to P site and causes misreading of mRNA
Staph aureus: - ANSWER-G+, HM (skin, hair, nose, throat), 30% of population is colonized, ubiquitous. MRSA (mecA). VRSA (d-ala to d-lac) III)
K. pneumoniae: - ANSWER-G-. HM. Ubiquitous. HAI. Leading cause of CA and HA pneumoniae. Resistance is through carbaenemases (NDM-1 and KPC-1) IV)
Chloramphenicol - ANSWER-binds to 50S and inhibits peptidyltransferase
Glycopeptides - ANSWER-Cell wall synthesis inhibitor
Quinolones - ANSWER-Inhibits DNA replication
Oxazolidinones - ANSWER-Binds to 50S ribosomal subunit and inhibits the initiation complex
Sulfonamides - ANSWER-DHPS inhibitor
Tetracycline - ANSWER-binding site overlaps partially with the aminoacyl- tRNA binding site leading to tRNA dissociation from the ribosome consequently blocking translation
Macrolides - ANSWER-antibiotics have high affinity for the 50S ribosomal subunit (bind to the same site as lincosamides) b. Bind to proximal end of the peptide exit tunnel leading to peptidyltransferase inhibition
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