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BIOL 2300 Exam 2 Quiz questions with correct answers With Complete Solution
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BIOL 2300 Exam 2 Quiz questions with correct answers With Complete Solution
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BIOL2300
Exam
2:
Quiz
Questions
A
boy
with
Klinefelter
syndrome
(47,XXY)
is
born
to
a
mother
who
is
phenotypically
normal
and
a
father
who
has
the
X-
linked
skin
condition
called
anhidrotic
ectodermal
dysplasia.
The
mother's
skin
is
completely
normal
with
no
signs
of
the
skin
abnormality.
In
contrast,
her
son
has
patches
of
normal
skin
and
patches
of
abnormal
skin.
(a)
Which
parent
contributed
the
abnormal
gamete?
(b)
Using
the
appropriate
genetic
terminology,
describe
the
meiotic
mistake
that
occurred.
Be
sure
to
indicate
in
which
division
the
mistake
occurred.
-
✔✔
-*The
father
must
have
contributed
the
abnormal
X-linked
gene.;
b.
Non-disjunction
must
have
occurred
during
meiosis
I.*
A
human
with
the
karyotype
49,
XXYY
forms
_______
Barr
bodies.
-
✔✔
-*1*
A
number
of
human-mouse
somatic
cell
hybrid
clones
were
examined
for
the
expression
of
specific
human
genes
linked
to
Alzheimer's
disease
and
the
presence
of
human
chromosomes.
The
results
are
summarized
in
the
following
table.
A
+
sign
indicates
the
gene
was
expressed
in
the
stated
hybrid
cell
clone;
a
-
sign
indicates
the
listed
gene
was
not
expressed
in
the
stated
hybrid
cell
clone.
The
second
chart
tells
you
which
chromosomes
are
present
in
each
hybrid
cell
clone.
-
✔✔
-a)
the
APP
gene
is
located
upon
chromosome
*21*
b)
the
pSEN1
gene
is
located
upon
chromosome
*14*
A
plaque
assay
is
performed
beginning
with
1
mL
of
a
solution
containing
bacteriophages.
This
solution
is
serially
diluted
4
times
by
combining
0.1
mL
of
each
sequential
dilution
with
9.9
mL
of
liquid
medium.
Then
0.1
mL
of
the
final
dilution
is
plated
in
the
plaque
assay
and
yields
28
plaques.What
is
the
initial
density
of
bacteriophages
in
the
original
1
mL?
Recall
that
initial
phage
density
=
(plaque
number/mL)
×
-
✔✔
-*2.8
x
10^16pfu/ml*
A
woman
who
sought
genetic
counseling
is
found
to
be
heterozygous
for
a
chromosomal
rearrangement
between
the
second
and
third
chromosomes.
Her
chromosomes,
compared
to
those
in
a
normal
karyotype,
are
diagrammed
below:
-
✔✔
-*The
chance
of
a
normal
child
is
approximately
one
in
two;
however,
half
of
the
normal
children
will
be
translocation
carriers.*
An
individual
has
the
following
genotype.
Gene
loci
(A)
and
(B)
are
15
cM
apart.
If
a
testcross
is
performed
on
this
individual
what
percentage
of
gametes
will
be
either
aB
or
Ab?
-
✔✔
-*85%*
Assume
that
a
cross
is
made
between
AaBb
and
aabb
plants
and
that
the
offspring
fall
into
approximately
equal
numbers
of
the
following
groups:
AaBb,
Aabb,
aaBb,
aabb.
These
results
are
consistent
with
________.
-
✔✔
-*independent
assortment*
Assuming
a
normal
number
of
autosomes,
what
would
be
the
sex
of
the
following:
XXY
mouse,
XXY
Drosophila
respectively?
-
✔✔
-*male,
female*
Bacteria
that
are
in
a
particular
physiological
state
to
become
transformed
are
called
________.
-
✔✔
-*competent* Cat
breeders
are
aware
that
kittens
expressing
the
X-linked
calico
coat
pattern
and
tortoiseshell
pattern
are
almost
invariably
females.
Which
one
of
the
following
statements
supports
this
conclusion?
-
✔✔
-*Since
females
normally
have
two
X
chromosomes,
random
X
inactivation
during
development
of
a
heterozygous
female
will
create
a
mottled
pattern.
Normal
males
are
not
mottled,
because
they
only
have
one
X
chromosome
and
therefore
can
only
express
one
of
the
two
potential
X-linked
alleles.*
Describe
the
cytological
observation
that
suggests
that
crossing
over
occurs
during
the
first
meiotic
prophase.
-
✔✔
-*homologous
chromosomes
pair
side
by
side*
Drosophila
may
be
monosomic
for
chromosome
4,
yet
remain
fertile.
A
recessive
mutant
for
bent
bristles
is
identified
on
chromosome
4.
In
the
answer
choices,
b+
indicates
wild
type
bristles,
b
indicates
bent
bristles,
and
_(blank)
indicates
the
absence
of
a
chromosome
4.
The
following
cross
is
conducted
of
true-breeding
adult
flies:
monosomic
bent
bristles
×
diploid
normal
bristles
Select
all
answers
that
represent
F1
genotypes
produced
from
crossing
a
monosomic
bent
bristles
fly
with
a
fly
with
bent
bristles.
Both
parentals
are
assumed
true
breeding.
-
✔✔
-*_/b*
*b/b*
For
a
species
with
a
diploid
number
of
12,
indicate
how
many
chromosomes
will
be
present
in
the
somatic
nuclei
of
individuals
that
are
(a)
haploid,
(b)
triploid,
(c)
tetraploid,
(d)
trisomic,
and
(e)
monosomic.
Enter
your
answers
in
the
appropriate
blank
as
a
whole
number.
-
✔✔
-a)
*6*
b)
*18*
c)
*24*
d)
*13*
e)
*11*
Genes
X,
Y,
and
Z
are
linked.
Crossover
gametes
between
genes
X
and
Y
are
observed
with
a
frequency
of
26%,
and
crossover
gametes
between
genes
Y
and
Z
are
observed
with
a
frequency
of
5%.
What
is
the
expected
frequency
of
double
crossover
gametes
among
these
genes?
(Hints:
1)
the
probability
of
one
single
crossover
AND
another
single
crossover
happening
at
the
same
time
reminds
me
of
a
rule
I
once
heard
of.)
-
✔✔
-*1.3%*
Genetic
distances
within
a
given
linkage
group:
-
✔✔
-*cannot
exceed
50
cm*
*can
only
be
determined
for
alleles
located
on
the
same
chromosome*
*are
more
accurate
if
genes
are
located
closer
together*
How
can
the
order
of
three
linked
genes
(A,
B,
and
C)
on
the
same
chromosome
be
determined?
-
✔✔
-*look
for
double-crossover
phenotypes
involving
the
wild-type
and
mutant
alleles
of
genes
A,
B,
and
C*
How
do
we
know
that
specific
genes
are
linked
on
a
single
chromosome,
in
contrast
to
being
located
on
separate
chromosomes?
-
✔✔
-*the
genes
segregate
together
during
gamete
formation*
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