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APEA ENDO WITH COMPLETE QUESTIONS AND ACCURATE ANSWERS RATED A+
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APEA ENDO WITH COMPLETE QUESTIONS AND ACCURATE ANSWERS RATED A+
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APEA ENDO WITH COMPLETE QUESTIONS AND ACCURATE ANSWERS RATED A+ The combination of metformin (Glucophage) and glyburide (Diabeta) for the tx of T2DM is: Correct Answer highly efficacious with a moderate risk of hypoglycemia A pt is receiving a fast -acting insulin to decrease post -prandial blood sugars. If the bedtime blood sugar is elevated, the pt should be advised to increase the fast -acting insulin dose at: Correct Answer Dinner -onset of rapid acting is 15 mins Which of the following is a rapid -acting insulin? Correct Answer Aspart (Novolog) Pts should be advised to take glimepiride (Amaryl): Correct Answer In the morning with breakfast -or 1st meal of the day, long acting sulfonylurea Which statement about metformin (Glucophage) is correct? Correct Answer It should be temporarily discontinued for radiologic studies with iodinated contrast -may result in acute alteration of kidney function Insulin glargine (Lantus) is NOT indicated in the tx of: Correct Answer Pediatric pts with T2DM Sodium -glucose co -transporter 2 (SGLT2) inhibitors reduce blood glucose by: Correct Answer Increasing urinary glucose excretion Pioglitazone hydrochloride (Actos) is contraindicated in pts with: Correct Answer heart failure -can cause dose -related fluid retention Alpha -glucosidase inhibitors such as acarbose (Precose) are contraindicated in pts with: Correct Answer Inflammatory bowel disorders -delays absorption of carbs following a meal In addition to hemoglobin A1C, pts receiving metformin (Glucophage) should be monitored for: Correct Answer Renal function, liver function, and vit B12 levels The mechanism of action of methimazole (Tapazole) is to: Correct Answer Block synthesis of thyroxine and triiodothyronine (T3) -readily absorbed in the GI tract, metabolized in the liver, and excreted in the urine Which of the following medications may cause gynecomastia? Correct Answer Enalapril (Vasotec) -ACE inhibitors may cause gynecomastia A pt is started on a sulfonylurea (i.e. glyburide). The NP informs the pt that sulfonylureas are likely to: Correct Answer Reduce microvascular events -also low in cost Disadvantages -produce hypoglycemia and cause weight gain Thiazolidinedione (TZD) medications: Correct Answer Increase insulin sensitivity -by acting on adipose, muscle & liver to increase glucose utilization and decrease glucose production Pts taking dipeptidyl -peptidase -4 (DDP -IV) inhibitors for the tx of T2DM do NOT routinely need to be monitored for: Correct Answer Weight loss -Januvia, Onglyza, Tradjenta not likely to cause weight loss or weight gain The expected hemoglobin A1V reduction for pts who are started on dipeptidyl -peptidase -4 (DDP -IV) inhibitors such as sitagliptin (Januvia) is: Correct Answer 0.6% DDP -IV inhibitors such as alogliptin (Nesina): Correct Answer Suppress glucagon secretion and increase insulin secretion Sulfonylurea -stimulate the release of insulin from functioning beta cells Biguanides -decrease hepatic glucose production, decrease intestinal absorption of glucose, and improve insulin sensitivity Prior to the admin of methimazole (Tapazole) the NP should obtain a baseline: Correct Answer CBC -tx for hyperthyroidism, CBC & liver profile should be obtained A pt is started on exenatide (Byetta) for T2DM. Byetta should be d/c'd if the pt exhibits: Correct Answer Persistent abd pain, radiating to the back -monitored for sx of acute pancreatitis Sulfonylureas such as glyburide (Micronase) are extensively metabolized: Correct Answer In the liver -primarily by CYP 450 A 48-year-old pt is started on metformin (Glucophage) for T2DM. The maximum expected hemoglobin A1C reduction after initiation of this medication is: Correct Answer 2%- usual expected decrease in A1C is 1 -2% Insulins recommended for use in insulin pump delivery systems include: Correct Answer Apidra & Humalog -only rapid acting insulins are safe for continuous IV use The generic name for Victoza is: Correct Answer Liraglutide -GLP-
1 agonists
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