100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
Previously searched by you
NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS MIDTERM AND FINAL EXAM STUDY GUIDE| 300 QUESTIONS AND 100 % CORRECT ANSWERS | RATED A QUIZ BANK | LATEST, 2024 / 2025| CHAMBERLAIN COLLEGE$25.99
Add to cart
NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS MIDTERM AND FINAL EXAM STUDY GUIDE| 300 QUESTIONS AND 100 % CORRECT ANSWERS | RATED A QUIZ BANK | LATEST, 2024 / 2025| CHAMBERLAIN COLLEGE
4 views 0 purchase
Course
NR565 ADVANCED PHARMACOLOGY
Institution
NR565 ADVANCED PHARMACOLOGY
NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS
MIDTERM AND FINAL EXAM STUDY GUIDE| 300 QUESTIONS
AND 100 % CORRECT ANSWERS | RATED A QUIZ BANK |
LATEST, 2024 / 2025| CHAMBERLAIN COLLEGE
1 | P a g e NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS MIDT ERM AND FINAL EXAM STUDY GUIDE| 300 QUESTIONS AND 100 % CORRECT ANSWERS | RATED A QUIZ BANK | LATEST, | CHAMBERLAIN COLLEGE The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. - CORRECT ANSWER >>>Pharmacokinetics The study of what the drug does to the body - CORRECT ANSWER >>>Pharmacodynamics Rate of dissolution Surface area Blood fl ow Lipid solubility pH partitioning - CORRECT ANSWER >>>Factors Affecting Drug Absorption 2 | P a g e Blood flow to tissues Ability to exit the vascular system Blood -brain barrier Protein -binding capacity - CORRECT ANSWER >>>Factors Affecting Drug Distribution subst ances that are foreign to the body, usually synthetic chemical compounds; medications are a common example - CORRECT ANSWER >>>Xenobiotics xenobiotic -metabolizing enzymes necessary for the production of cholesterol and steroids and the detoxification of chemicals and drug metabolism. - CORRECT ANSWER >>>Cytochrome P450 (CYP450) responsible for phase 1 metabolism in which drugs are oxidized, reduced, or hydrolyzed - CORRECT ANSWER >>>Function of Cytochrome P450 (CYP450) Oxidation; Reduction; Hydrolysis - CORRECT ANSWER >>>Phase 1 Metabolism of Drugs via P450 -Drug becomes completely inactive -Drug becomes partially inactive but one or more metabolites remain active 3 | P a g e -Original drug is not pharmacologically active but one metabolite remains active - CORRECT ANSWER >>>Three possible outcomes of phase 1 drug metabolism. Medications that can increase the rate of another drug's metabolism by elev ating CYP450 enzyme activity via increasing enzyme synthesis. decreasing the concentration of the "parent drug" - CORRECT ANSWER >>>CYP450 Inducers CRAPGPS Carbamazepine Rifampin Alcohol Phenytoin Griseofulvin Phenobarbital Sulfonylureas - CORRECT ANSWER >>>CYP450 Inducer Medications Medications that inhibit the metabolic activity of one or more of the CYP450 enzymes. Higher risk for toxicity; prolongs the pharmacological effect of the "parent drug". - CORRECT ANSWER >>>CYP450 Inhibitors VISACKGQ Valproa te Isoniazid Sulfonamides Amiodarone 4 | P a g e Chloramphenicol Ketoconazole Grapefruit Juice Quinidine - CORRECT ANSWER >>>CYP450 Inhibitor Medications -potentially Inappropriate Medication (PIM) use in older adults -potentially Inappropriate Medication (PIM) use in older adults due to medication -disease or medication -syndrome interactions that may exacerbate the disease or syndrome -medications to be used cautiously in older adults -clinically significant drug intera ctions that should be avoided in older adults -medications to be avoided or dosage decreased in the presence of impaired kidney function in older adults - CORRECT ANSWER >>>Beers Criteria when one medication systemically alters the potency of another medi cation. - CORRECT ANSWER >>>Pharmacokinetic Interactions result of a change due to one medication's effect on another medication's route of entry into the body. - CORRECT ANSWER >>>Absorption Interaction caused by the amount of unbound/free medications a vailable at the various target sites. - CORRECT ANSWER >>>Distribution Interaction
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller keithdaniel. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $25.99. You're not tied to anything after your purchase.
