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NR565/ NR 565 MIDTERM EXAM 2 VERSIONS ADVANCED PHARMACOLOGY CARE OF THE FUNDAMENTALS EXAM QUESTIONS AND VERIFIED ANSWERS ( LATEST UPDATE) - CHAMBERLAIN$27.99
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NR565/ NR 565 MIDTERM EXAM 2 VERSIONS ADVANCED PHARMACOLOGY CARE OF THE FUNDAMENTALS EXAM QUESTIONS AND VERIFIED ANSWERS ( LATEST UPDATE) - CHAMBERLAIN
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Course
NR565 ADVANCED PHARMACOLOGY
Institution
NR565 ADVANCED PHARMACOLOGY
NR565/ NR 565 MIDTERM EXAM 2 VERSIONS ADVANCED
PHARMACOLOGY CARE OF THE FUNDAMENTALS EXAM
QUESTIONS AND VERIFIED ANSWERS ( LATEST
UPDATE) - CHAMBERLAIN
NR565/ NR 565 MIDTERM EXAM 2 VERSIONS ADVANCED
PHARMACOLOGY CARE OF THE FUNDAMENTALS EXAM
QUESTIONS AND VERIFIED ANSWERS ( LATEST
UPDA...
NR56 5/ NR 565 MIDTERM EXAM 2 VERSIONS ADVANCED PHARMACOLOGY CA RE OF THE FUNDAMENTALS EXAM QUESTI ONS AND VERIFIED ANSWERS ( 2024 - 2025 LATEST UPDATE) - CHAMBERLAIN Which Drugs can APRNS p rescribe - CORRECT ANSWER >>>DEA license will allow for prescribing schedules 2 -5 there can be restrictions as noted in collaborative agreement. maybe facility/state dependent. Who determines and regulates prescriptive authority? - CORRECT ANSWER >>>determines: APRNS can prescribe without limitation and is state dependent. It is regulated by health professional board state board of nursing or state board of medicine or pharmacy. federal government controls regulation but no control over prescriptive authority. How does limited prescriptive authority impact patients within the healthcare system? - CORRECT ANSWER >>>Creates numerous barriers to quality aff ordable and acessible patient care. Key responsibilities to prescribing? - CORRECT ANSWER >>>Do not prescribe to family/friends or yourself. document a thorough history and physical examination. Include discussions with patient about risk factors and side effects, medication monitoring or titration. if additional consults are made, know limitations, keep rx pads in a safe place confirm allergies verify medication list dont let insurance dictate quality of RN charting is key. what should be used to make prescribing decisions? - CORRECT ANSWER >>>Cost, availability, current practice guidelines, medication interactions with food side effects need for monitoring how drug is metabolized. special populations. ask if prescriptions ar e cost prohibitive. Pharmacokinetics - CORRECT ANSWER >>>what the body does to the drug Pharmacodynamics - CORRECT ANSWER >>>what the drug does to the body physilogic changes that can affect the pharmaconetics in older adults. - CORRECT ANSWER >>>absorp tion: inc gastric PH decreased absorptive surface area and dec splanchnic blood flow. dec GI motility delayed gastric emptying distribution: inc body fat dec lean body mass dec total body water serum albumin cardiac output. metabolism: dec hepatic blood fl ow mass and activity of hepatic enzymes. excretion: decreased renal blood flow GFR tubular secretion and number of nephrons. reducing adverse drug reaction in older adults? - CORRECT ANSWER >>>Thorough drug history go low and slow with initiating drug the rapy monitor clinical responses and plasma levels use simple medication regimen, monitor drug interaction review drug therapy dispose old medications promote adherence use beers criteria. Beers Criteria - CORRECT ANSWER >>>A list of medications that are g enerally considered inappropriate when given to elderly people impacts of polypharmacy - CORRECT ANSWER >>>using 5 or more medications daily leads to possible drug interactions . CYP450 inhibitors - CORRECT ANSWER >>>CRACK AMIGOS Chloramphenicol Ritonavir (protease inhibitor) Amiodarone Ciprofloxacin Ketocanazole (and other azoles) Acute alcohol use Valproate Isoniazid Grapefruit Juice Sulfonamides CYP450 inhibitors function - CORRECT ANSWER >>>slow down the metabolic activity of specific enzymes, causin g a decrease in the rate/extent of metabolism of other drugs that are substrates for those same enzymes this can cause drug toxicity. CYP450 inducers - CORRECT ANSWER >>>barbituates, griseofulvin, carbamazepine, rifampin, st. john wart, chronic alcoholism, phenytoin (CRAP GPS) CYP450 inducers function - CORRECT ANSWER >>>increase medication metabolism. act on the liver to stimulate enzyme synthesis If CYP450 is induced, what is the effect on medication metabolism? - CORRECT ANSWER >>>drug may not achieve therapeutic effects When patients have a poor metabolism phenotype? - CORRECT ANSWER >>>slows or increases absorption ex; plavix clots and inc platelets pregnancy hepati c metabolism increases and dec bowel motility increases absorption of the drug. newborns the drug metabolizing capacity is low, children by the age of 1 are similar to adults but they can be metabolized quickly an increase or reduction in dosing may be nee ded. geriatric rates of hepatic drug metabolism tend to decline with age half life of drugs maybe increased and prolong responses.
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