Summary
Summary Insulin and its receptors
- Course
- Institution
If you want to understand how insulin receptors work read this
[Show more]
Seller
Follow
qusaielfires
Content preview
INSULIN RECEPTOR (Enzyme receptor) Two parts: one in and one outside of the cell. (Located in membrane)1. Insulin binds to the 2 alpha subunit of the receptor on the outside of the cell, bringing them together.
2. The 2 beta subunits of the receptor on the inside of the cell work together to phosphorylate thyrosine residues.
3. This leads to processes favouring the transport of glucose, fatty acids and amino acids into the cell.
7
NUCLEAR HORMONE RECEPTOR: (located in the cell)
1. Lipophilic hormones come from the blood stream (attached to globolins) and are released from transporting protein.
2. Hormone travels via the membrane to the cytoplasm.
3. Hormone attaches to receptor, causing a change in the confirmation of the receptor.
4. 2 Hormone receptor complexes bind in the nucleus to the structure of DNA in the hormone response element.
5. This activates RNA polymerase, which will synthesize a messenger RNA.
6. mRNA exits nucleus, traveling to ribosomes where protein synthesis occurs.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller qusaielfires. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $6.37. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
64438 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now