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Nursing Pharmacology Chapter 1 Drug Action Questions And Answers With Correct Answers (GRADED A+) Latest Update 2024/2025. $10.49   Add to cart

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Nursing Pharmacology Chapter 1 Drug Action Questions And Answers With Correct Answers (GRADED A+) Latest Update 2024/2025.

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Nursing Pharmacology Chapter 1 Drug Action Questions And Answers With Correct Answers (GRADED A+) Latest Update 2024/2025.

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Nursing Pharmacology Chapter 1 Drug Action Questions
And Answers With Correct Answers (GRADED A+) Latest
Update 2024/2025.
A drug taken by mouth goes through 3 phases - ANSWER pharmaceutic (dissolution),
pharmacokinetics and pharmacodynamic

In the pharmaceutic phase (1st phase) the drug becomes a - ANSWER solution so that it can
cross the biologic membrane

When a drug is administered parenterally such as subQ, IM or IV routes, there is no - ANSWER
pharmaceutic phase

The pharmacokinetic phase (2nd phase), is composed of 4 processes - ANSWER absorption,
distribution, metabolism (biotransformation) and excretion (elimination)

In the pharmacodynamic phase (3rd phase), - ANSWER a biologic or physiologic response
results

Approximately ______% of drugs are taken by mouth - ANSWER 80

In the GI tract, drugs need to be in _________ so they can be absorbed - ANSWER solution

Dissolution - ANSWER a drug in solid form (tablet or capsule) must disintegrate into small
particles to dissolve into a liquid

Tablets are not ______% drug - ANSWER 100

The 2 pharmaceutic phases are - ANSWER disintegration and dissolution

Excipients - ANSWER are fillers and inert substances, that are used in drug preparation to allow
the drug to take on a particular size and shape and to enhance drug dissolution

Infants have a higher ______ than those of adults; therefore infants can absorb more "penicillin" -
ANSWER pH (alkaline); "penicillin" is poorly absorbed by the GI tract because of gastric acidity,
therefore ionic potassium or sodium salt is usually added

Disintegration - ANSWER is the breakdown of a tablet into smaller particles

Dissolution - ANSWER is the dissolving of the smaller particles in the GI fluid before absorption

Rate limit - ANSWER is the time it takes the drug to disintegrate and dissolve to become
available for the body to absorb it

Drug in liquid form are more _____ available for GI absorption than are solids - ANSWER rapidly

"GENERALLY", drugs are both disintegrated and absorbed faster in _______ fluid with a pH of __ or ___
rather than in alkaline fluids - ANSWER acidic; 1 or 2

, Very young and older adults tend to have less gastric _____ - ANSWER acidity; therefore drug
absorption is slower via GI tract

Enteric coated drugs resist _________ - ANSWER disintegration, in the acid of the stomach;
therefore disintegration does not occur until the drug reaches the alkaline environment of the small
intestine

Enteric tablets can remain in the stomach for a long time; therefore their effect may be _______ -
ANSWER delayed

Enteric coated tablets or capsules and sustained release (beaded) capsules should not be _______.
Because this would alter the place and time of absorption. - ANSWER crushed

Food and water with GI drugs can - ANSWER slow down the absorption process or speed it up,
depending on the medication

Pharmacokinetics - ANSWER is the process of drug movement to achieve drug action;
absorption, distribution, metabolism (biotransformation) and excretion (elimination)

Absorption - ANSWER is the movement of drug particles from the GI tract to the body fluids by
passive absorption, active absorption or pinocytosis

Most oral drugs are absorbed into the surface of the _____ - ANSWER small intestine; through
the action of the extensive mucosal villi

Absorption is reduced if the villi are _______ in number. - ANSWER decreased; because of
disease, drug effect or the removal of the small intestine

Protein based drugs such as insulin and growth hormones are _______ in the small intestine by digestive
enzymes. - ANSWER destroyed

Passive absorption - ANSWER occurs mostly by diffusion (movement from higher concentration
to lower concentration). With the process of diffusion, the drug does not require energy to move across
the membrane

Active absorption - ANSWER requires a carrier such as an enzyme or protein to move the drug
against a concentration gradient. Energy is required for active absorption

Pinocytosis - ANSWER is a process by which cells carry a drug across their membrane by
engulfing the drug particles

The GI membrane is composed mostly of - ANSWER lipid (fat) or protein; therefore drugs that
are soluble pass rapidly through the GI membrane

Water soluble drugs need a ______ to pass through the GI membrane. - ANSWER carrier, either
enzyme or protein

Large particles in the GI tract can pass through the cell membrane if they are __________. -
ANSWER nonionized (have no positive or negative charge)

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