Prostaglandins... - increase capillary permeability, attract white blood cells, cause pain,
induce fever.
Inflammation is not a disease, it... - indicates an underlying problem
, The two types of drug classes for nonspecific inflammation are the... - non-steroidal
anti-inflammatory (NSAIDs) and corticosteroids.
Due to their serious long term effects... - corticosteroids are only used short term for
acute inflammation.
NSAIDs exhibit both... - anti-pyretic and analgesic effects as well
NSAIDs act by inhibiting... - the synthesis of prostaglandins.
NSAIDs block inflammation by... - inhibiting COX, an enzyme that synthesizes
prostaglandins
COX-1... - reduces gastric acid secretion, promoting renal blood flow, and regulating
smooth muscle tone in the blood vessels.
COX-2 is formed... - only after injury and promotes inflammation.
Most adverse effects from ibuprofen and aspirin are due to... - the blocking of COX-1
Aspirin belongs to the chemical family called... - salicylates
Aspirin is a potent inhibitor of... - thromboxane which is secreted by platelets
Salycism is a syndrome that includes symptoms such as... - tinnitus, dizziness,
headache, and excessive sweating.
Children under 19 should never be administered aspirin if they have signs of fever, flu,
or chicken pox for risk of... - Reye's syndrome
Ibuprofen and a lrage number of ibuprofen like drugs are... - NSAIDs
Aspirins work by... - inhibiting both COX-1 and COX-2 REVERSIBLY
The most common side effects of NSAIDs are... - nausea and vomiting.
Patients with CKD typically receive... - acetaminophen for pain or fever rather than
NSAIDs
What is the only COX-2 inhibitor still on the market? - Celebrex
Corticosteroids are natural hormones produces in the body by the... - adrenal cortex
and effect almost every cell in the body.
Corticosteroids inhibit... - the biosynthesis of prostaglandins.
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