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7
2 - body is made up of ___% water, ___% proteins, other solutes ___%.
albumin, globulins, clotting factors/proteins - plasma includes about 50-55% of the blood
volume. Plasma proteins include? (3)
Albumin - helps control oncotic pressure
globulins - Carrier proteins and immunoglobulins (antibodies)
clotting factors/ proteins - used to promote coagulation, mainly fibrinogen
erythrocytes, leukocytes, platelets - cellular components of in the hematologic system
(3)
Erythrocytes - -red blood cells, most abundant cells in blood
-responsible for tissue oxygenation
-bioconcavity and reversible deformity
-life cycle is between 100-120 days
Leukocytes - -white blood cells
-defend against infection and remove debris
-act in the tissues but are transported by circulation
-many diff types, each with their own important action.
Thrombocytes - -platelets
-they are irregularly shaped cytoplasmic fragments and are essential for blood
coagulation and control of bleeding
metabolism
microorganisms
acid-base - Chief function of the cells in the hematologic system:
-deliver substances needed for cellular ___
-remove wastes
-defense against ___ and injury
-maintenance of ___ balance
bone marrow - Soft, spongy tissue found in the cavities of bones, primarily responsible
for the production of blood cells through a process called hematopoiesis. Red ___
produces red and white blood cells, as well as platelets.
, lymphatic system - Comprises lymph nodes, lymph vessels, and lymphoid organs. It
plays a crucial role in filtering and draining lymph (a clear fluid containing white blood
cells) from each region of the body, helping to remove waste products and pathogens.
spleen - Acts as a blood filter, removing damaged blood cells and foreign particles. The
spleen also stores platelets and white blood cells and is involved in the immune
response.
blood clot - a meshwork of protein strands that stabilizes the platelet plug and traps
other cells, such as erythrocytes, phagocytes, and microorganisms
Fibrinolysis
major
Plasmin - The Fibrinolytic System:
-___ is initiated by the binding of plasminogen to fibrin.
-Although tissue plasminogen activator (t-PA) initiates intravascular fibrinolysis,
urokinase plasminogen activator (u-PA) is the ___ activator of fibrinolysis in tissue
(extravascular).
-___ digests the fibrin into smaller soluble pieces (fibrin degradation products). u-PAR,
Urokinase-like plasminogen activator receptor.
fibrinolytic system -
homeostasis - once the ___ is obtained, the clot is no longer needed.
shorten
platelets - Clot retraction:
-fibrin stands ___; become denser and stronger to approximate the edges of the injured
vessel and site of injury
-facilitated by large numbers of ___ within the clot
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