aminoglycosides MOA - ✔✔binds to bacteria, attaches to the ribosomal 30's & 50's subunit site
irreversable and inhibits protein synthesis. (Bacteriocidal)
anit-fungal MOA (dermatophytic) - ✔✔binds to infected keratinized tissue preventing the fungus from
invading the healthy tissue. (fungistatic - Griseofulvin)
Anit-fungals - ✔✔nystatin
ketoconazole
amphotericin B
griseofulvin
miconazole IV
%
anitbiotics effects on cancer - ✔✔Cell-cycle specific for the G2 phase. During this phase cells are
preparing for mitosis.
anthelmintics MOA - ✔✔paralyzes parasites/worms in the intestines and normal peristalsis
evacuates the parasites from the GI tract.
anti-fungal MOA (systemic) - ✔✔binds to fungal membrane producing a change in the cell's
permeability causing nutrients and ions to leak out leading to cell destruction. (fungicidal -
Amphotericin B)
, Anti-metabolites & Plant extracts - ✔✔Which of the following anti-neoplastics are cell cycle specific?
anti-metabolites MOA - ✔✔Inhibits DNA synthesis in the S phase when the cell is synthesizing DNA.
Madrases as a normal metabolite (aka: folic acid, purine, pyrimidine) and inhibits enzymes that are
essential to the synthesis of RNA and DNA.
Antibiotic - ✔✔Drug that interfere with the life cycle of a pathogen, making it incapable of
reproducing and sometimes resulting in cell death of the pathogen
Bacteria - ✔✔Single cell organism found virtually every where
Bacteriocidal - ✔✔Drug that kills a single celled organism
Bacteriostatic - ✔✔Drug that limits the growth of a single celled organism
benign - ✔✔a tumor that does not destroy or invade tissues around it, they are not cancerous and do
not reproduce harmful effects.
Cancer drugs - ✔✔etoposide
mechlorethamine
megestrol
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller EXAMQA. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $11.49. You're not tied to anything after your purchase.