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Exam (elaborations)

Complete BOC ASCP prep Questions and Answers

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  • BOC ASCP

151) What is the formula for calculating the dilution of a solution. ~ V1 x C1 = V2 x C2 V1 is the volume C1 is concentration of sol 1 V2 is vol of the diluted solution C2 is conc of diluted solution 241) To confirm a serum antibody specificity identified as anti-P1, a neutralization stud...

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  • August 5, 2024
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Questions and Answers
151) What is the formula for calculating the dilution of a solution.


✓~ V1 x C1 = V2 x C2

V1 is the volume

C1 is concentration of sol 1

V2 is vol of the diluted solution

C2 is conc of diluted solution




241) To confirm a serum antibody specificity identified as anti-P1, a neutralization

study was performed and the following results obtained:

serum + P1 substance = NEGATIVE

serum + saline = NEGATIVE

What conclusion can be made from these results.

,✓~ anti-P1 cannot be confirmed due to the results of the negative control

(For neutralization studies to be valid, the saline dilutional control must be reactive. Since

neutralization studies involve adding a substance to the patient's plasma, nonreactivity in

test tubes may be due to simple dilution. The saline control acts as the dilutional control and

must be reactive. When the saline control is reactive, then if the tube with the substance is

nonreactive, the interpretation that neutralization has occurred is made. If it is reactive,

neutralization did not occur.)




278) The most sensitive test for the initial diagnosis of cryptococcal disease is:


✓~ Cryptococcal latex antigen test is more sensitive than staining methods




308) Which of the following factors is used only in the extrinsic coagulation pathway?


✓~ Factor VII




8) Shown above is a Levy-Jennings quality control chart, which represents control

values for 13 consecutive analyses for a particular serum constituent. If the 14th

value is below the —2 SD limit, which of the following should be done?


✓~ analysis system should be checked for a deteriorating component




202) A 1 yr. old girl with a hyperlipoproteinemia and lipase deficiency has the

following lipid profile:

cholesterol = 300 mg/dL

LDL increased

,HDL decreased

triglycerides = 200 mg/dL

chylomicrons present

A serum specimen from this patient that was refrigerated overnight would most likely

be:


✓~ The chylomicrons, present as a thick homogenous cream layer, may be observed

floating at the plasma surface.




1) Following overnight fasting, hypoglycemia in adults is defined as a glucose of:


✓~ <45mg/dL (<2.5mmol/L)




3) The preparation of a patient for standard glucose tolerance testing should include:


✓~ high carb diet for 3 days




4) If a fasting glucose was 90 mg/dL, which of the following 2 hr. postprandial

glucose result would most closely represent normal glucose metabolism?


✓~ 100 mg/dL (5.5 mmol/L)




5) A healthy person with a blood glucose of 80 mg/dL (4.4 mmol/L) would have a

simultaneously determined cerebrospinal fluid glucose value of:


✓~ 50 mg/dL (2.3 mmol/L)

, 6) A 25 yr. old man became nauseated and vomited 90 mins after receiving a

standard 75 g carbohydrate dose for an oral glucose tolerance test. The best course

of action is to:


✓~ draw blood for glucose and discontinue the test




7) Cerebrospinal fluid for glucose assay should be:


✓~ analyzed immediately




8) Which of the following 2 hr. postprandial glucose values demonstrates

unequivocal hyperglycemia diagnostic for diabetes mellitus?


✓~ 200 mg/dL (11.0 mmol/L)




10) A 45 yr. old woman has a fasting serum glucose concentration of 95 mg/dL (5.2

mmol/L) and a 2 hr. postprandial glucose concentration of 105 mg/dL (5.8 mmol/L).

The statement which best describes this patient's fasting serum glucose

concentration is:


✓~ normal; reflecting glycogen breakdown by the liver




9) Serum levels that define hypoglycemia in pre-term or low birth weight infants are:


✓~ lower than adults

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