Questions and 100% Correct Answers
5 advantages of oral sedation: - Answer 1. universal acceptability
2. ease of administration
3. low cost
4. decreased incidence/severity of adverse reactions
5. no needles, syringes, equipment, or specialized training
________ is the most variable non-titrable sedation technique - Answer oral sedation
7 disadvantages of oral sedation: - Answer 1. relies on patient compliance
2. long latent period (30 min, peak at 60 min)
3. unreliable drug absorption in GI tract
4. inability to titrate effect
5. inability to lighten/deepen level of sedation
6. prolonged duration of action
7. oversedation can occur
Define the "First Pass Effect" - Answer drugs are partially metabolized in the liver before
ever reaching systemic circulation
Which drugs are absorbed more rapidly: lipid-soluble or non-lipid-soluble? - Answer
lipid-soluble
, Which drugs are able to freely diffuse and which are more poorly absorbed: acidic or
alkaline? How does this change in a basic environment such as the intestines? - Answer
acidic = freely diffuse (LA)
alkaline = poorly absorb (codeine)
opposite in a basic environment
4 types of oral sedatives used in dentistry: - Answer 1. sedative anti-anxiety drugs
2. sedative hypnotics
3. antihistamines
4. opioid analgesics
__________ are the most common type of sedative drug used in dentistry - Answer
benzodiazepines
Why are benzodiazepines the preferred drug type in dentistry? - Answer wide dosage
range of therapeutic activity with a wide margin of safety
3 main actions of benzodiazepines: - Answer 1. CNS effects (taming, disinhibition)
2. muscle relaxant
3. anticonvulsivant
Which 3 benzodiazepines are commonly used in dentistry as pre-treatment anxiolytics: -
Answer 1. Diazepam
2. Oxazepam
3. Aprlaozam