NUR 325 Exam 1 ASU Questions With
Correct Answers
Generic name - answernot capitalized, less expensive
brand name - answercommercial name, capitalized
what are the different types of oral medications? - answerliquid, tablet, capsule, powder
which form absorbs the fastest? - answerliquid
which...
Generic name - answer✔✔not capitalized, less expensive
brand name - answer✔✔commercial name, capitalized
what are the different types of oral medications? - answer✔✔liquid, tablet, capsule, powder
which form absorbs the fastest? - answer✔✔liquid
which form absorbs the slowest? - answer✔✔enteric coated tablet
what are the 3 ways a drug can be delivered parenterally? - answer✔✔intravenously,
subcutaneously, intramuscularly
which parenteral drug is fastest? - answer✔✔IV
pharmacokinetics - answer✔✔movement of drugs from site of administration to various tissues
1st pass effect - answer✔✔some of the drugs when passed though the liver may deactivate —>
reduces effect of drugs
bioavailability - answer✔✔amount of oral drug after passing through the liver
parenteral drugs - answer✔✔does not get affected by 1st pass effect because it goes directly to
the vein or tissue
what factors affect distribution to different parts of the body? - answer✔✔-movement of drug by
circulatory system to intended site of action
-drugs enter the blood after they absorb through intestinal wall or alveoli in lungs or after
direct/indirect injection
-liver, heart, kidneys receive most of drugs because of their rich drug supply
-bones or areas with natural barrier (brain) won't receive as much of the drug
Metabolism (biotransformation) - answer✔✔The biochemical alteration of a drug into an
inactive metabolite, a more soluble compound, a more potent active metabolite, or a less active
metabolite
biotransformation - answer✔✔when a drug is chemically altered during metabolism
EXAM STUDY MATERIALS July 26, 2024 9:30 AM
, Where does metabolism take place? - answer✔✔liver
half life - answer✔✔time it takes for a drug that enters the body to decrease in half
onset - answer✔✔the time it takes for the drug to elicit a therapeutic response
peak - answer✔✔The time it takes for a drug to reach its maximum therapeutic response
duration - answer✔✔time the drug lasts without additional doses
peak level - answer✔✔The maximum concentration of a drug in the body after administration,
usually measured in a blood sample for therapeutic drug monitoring.
trough level - answer✔✔The lowest concentration of drug reached in the body after it falls from
its peak level, usually measured in a blood sample for therapeutic drug monitoring.
Why is peak & trough important? - answer✔✔must maintain at a therapeutic level in the blood
in order to be effective
Pharmacodynamics - answer✔✔Biochemical changes that occur in the body as a result of taking
a drug
adverse reactions - answer✔✔a list of possible unpleasant or dangerous secondary effects other
than the desired effect
Therapeutic effect - answer✔✔The desired or intended effect of a particular medication.
"off-label" - answer✔✔the use of drugs for unapproved indication or in an unapproved age
group, dosage, or route of administration
most severe adverse reaction - answer✔✔anaphylactic shock
clinical manifestations of anaphylactic shock - answer✔✔swelling of eyes, mouth, face, and
throat, difficultly breathing, wheezing, rapid HR, extremely low BP, eventually cardiac arrest
drug tolerance - answer✔✔body decreased response to a drug over a period of time or repeated
use
cumulative effect - answer✔✔When the body cannot completely metabolize and excrete one
drug dose before next dose is given
drug toxicity - answer✔✔excessive doses result in negative physiologic effects (can be
irreversible) may lead to OVERDOSE
precautions - answer✔✔benefits outweigh the risk
Contraindications - answer✔✔drugs the provider should NOT prescribe because they have
potential to cause serious or life-threatening adverse effects
EXAM STUDY MATERIALS July 26, 2024 9:30 AM
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