2024 PHARMACOLOGY WEEK 1
EXAM QUESTIONS WITH
CORRECT ANSWERS
The prescriber orders a new drug over the telephone for a nursing home
patient who has symptoms of a urinary tract infection. The order is for
Gantanol, 2 g now and then 1 g every 12 hours for the next 10 days. What
further information is most important for the nurse to obtain from the
prescriber?
A. "How many refills are needed?"
B. "Do you want the drug given orally or intravenously?"
C. "Which brand of drug should be given, or is this a generic drug?
D. "Does this drug need to be given with a meal or on an empty stomach?" -
CORRECT ANSWERS-B. "Do you want the drug given orally or intravenously?"
The route of administration was not indicated in the original order
A patient is to receive an acetaminophen (Tylenol) suppository for an
elevated temperature of 102.8° F. The nurse must take the following actions
EXCEPT
A. Ask if the patient is having any diarrhea.
B. Put on a pair of sterile gloves.
C. Place the patient in the Sims' position. Ask the patient to take a deep
breath and bear down.
D. Push the suppository into the rectum about 1 inch. - CORRECT ANSWERS-
B. Put on a pair of sterile gloves
This would be a nice touch, but all that is required is clean gloves. When
patient has diarrhea, it is not appropriate to give drug rectally. Asking patient
to bear down can ease insertion by relaxing anal muscles and allowing
suppository passing, besides, when patient is bearing down, the presence of
stool can be identified. The suppository won't be effective if it is buried in the
feces. Depth of insertion makes difference in route of administration (enteral
vs. percutaneous or rectal), which in turns affects the amount of absorption.
Drug given through enteral route is affected by first pass loss, while drug
given through rectal is not.
, It is a concept used to measure safety of drugs, and it is the ratio of the
lethal dose divided by the therapeutic dose for 50% of population. -
CORRECT ANSWERS-Therapeutic Index
This concept defines the time span needed to eliminate 50% of drug dose -
CORRECT ANSWERS-Half life
A drug-induced birth defect - CORRECT ANSWERS-Teratogenic effect
How the medication produces the desired therapeutic effect - CORRECT
ANSWERS-Mechanism of action
It is expected that the nurse will question the health care provider if a drug
with a t(1/2) of a >24 hour drug is ordered to be given more than how often.
A. Once daily
B. Every other day
C. Twice weekly
D. Once weekly - CORRECT ANSWERS-A. Once daily
t(1/2) is half live. If the half life of a drug is 24 hours it should be only given
once daily. If the half life is 6 hours, it should only be given every 6 hours
and so on...
The nurse notices that one of the client's drugs has a low therapeutic index.
What is the most important nursing implication of this?
A. A wide margin of safety
B. A narrow margin of safety
C. Measured 1 hour after administration
D. Measured 10 minutes after administration - CORRECT ANSWERS-B. A
narrow margin of safety.
Therapeutic index refers to the level at which a drug is more helpful than
harmful. If there is a low therapeutic index, then there is a narrow margin of
safety.
Which of the following nurse actions should be most appropriate for ensuring
client safety with a medication that has a low therapeutic index?
A. Monitoring a patient's urine output
B. Assessing vital signs hourly
C. Maintaining strict isolation precautions
D. Monitoring serum peak and trough levels - CORRECT ANSWERS-D.
Monitoring serum peak and trough levels.
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