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NSG552 Psychopharmacology Exam 1 Questions and Answers (Update 2025)
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NSG552 Psychopharmacology Exam 1 Questions and Answers (Update 2025)
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NSG552 Psychopharmacology Exam 1Questions and Answers (Update 2025)
What are the 6 general principles of psychopharmacological
treatment? - Correct Answer ✅Safety
Tolerability
Efficacy
Practicality
Treatment accessibility
Treatment compliance
Pharmacokinetics - Correct Answer ✅How the drug moves in
the body. (ex. Where is it absorbed? How and where is it
metabolized? Where is it excreted?)
Pharmacodynamics - Correct Answer ✅What the drug does to
the body. (consider mechanism of action)
Define First-generation antipsychotics - Correct Answer
✅Referred to as Typical Antipsychotics. Most have strong
bond with D2 receptors only, cause EPS symptoms faster due
to prolonged receptor dissociation, have more dangerous side
effect profiles, have been around longer, more effective at
,NSG552 Psychopharmacology Exam 1
Questions and Answers (Update 2025)
treating positive symptoms, less expensive. (Ex. Haloperidol,
Chlorpromazine, Thioridazine, Fluphenazine)
Define Second-generation antipsychotics - Correct Answer
✅Referred to as Atypical Antipsychotics. Most have a weak
bond with D2 receptors and block serotonin receptors leading
to anti-depressive and anxiolytic effects. They cause less EPS
due to rapid receptor disassociation which leads to rapid
dopamine neurotransmission. Have less dangerous side effect
profiles but can cause metabolic syndromes, have been
around shorter time, more expensive, more effective at
treating negative symptoms but can treat positive symptoms
as well, long-acting injections available for several of these.
(Ex. Risperidone, Clozapine, Quetiapine, Aripiprazole,
Ziprasidone)
Extra Pyramidal Symptoms (EPS) - Correct Answer ✅Side
effects caused by certain antipsychotic medications, which
include: involuntary or uncontrollable movements. tremors.
muscle contractions.
, NSG552 Psychopharmacology Exam 1
Questions and Answers (Update 2025)
Tardive dyskinesia - Correct Answer ✅A neurological disorder
characterize by involuntary movement of the face and jaw.
Upregulation - Correct Answer ✅Occurs through chronic use
of antagonists which causes an increase in the number of
receptors, externalization of receptors, and increased
sensitivity of the receptors. Prolonged use of antagonist ->
Up-regulation of receptors -> Sudden withdrawal of
antagonist -> increased number of receptors and increased
sensitivity of receptors *YOU MUST GRADUALLY TAPER A
DRUG TO AVOID BINDING TO ALL NEW RECEPTORS FROM
UPREGULATION
Down regulation - Correct Answer ✅Occurs by chronic
exposure of agonists which causes decreased number of
receptors, internalization of receptors, and decreased
sensitivity of the receptors. Prolonged use of agonist ->
down-regulation of receptors -> decreased effectiveness of
agonist mediated clinical response.
You have two options:
1 Increase the drug dose OR 2 Switch to another drug(BEST
OPTION)
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