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MB ASCP Practice Exam Questions With Correct Answers 2024
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MB ASCP Practice Exam Questions With Correct Answers 2024
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MB ASCP Practice Exam Questions WithCorrect Answers 2024
Which mof mthe mfollowing mis mnot ma mcomponent mof ma mnucleotide?
Phosphate mgroup
Anti-codon
Ribose msugar
Nitrogen mbase m- mcorrect manswer.Anti-codon
According mto mChargaff's mrule mof mbase mpairing, madenine mpairs mwith: m- mcorrect
manswer.Thymine
What mgenes mwould mbe mscreened min ma mbreast mcancer mpanel? m- mcorrect manswer.HER2,
mERBB2, mBRCA1
Next mGeneration mSequencing muses: m- mcorrect manswer.Short msequence mreads
Purines mand mpyrimidines mdiffer mfrom meach mother min mthat: m- mcorrect manswer.Purines
mhave mtwo mrings; mpyrimidines mhave mone mring
The mpurines mare:
Cytosine mand muracil
Adenine mand mthymine
Thymine mand mcytosine
Adenine mand mguanine m- mcorrect manswer.Adenine mand mguanine
What mis mthe mrate mof mmutation mper mround mof mDNA mreplication?
1 min m1,000 mbase mpairs
1 min m10,000 mbase mpairs
1 min m1,000,000 mbase mpairs
1 min m1,000,000,000 mbase mpairs m- mcorrect manswer.1 min m1,000,000,000 mbase mpairs
The mrate mof mDNA mmigration mthrough man magarose mgel mduring melectrophoresis mdoes mnot
mdepend mon mwhich mof mthe mfollowing mfactors?
Net mcharge mof mthe mmolecule
Size mof mthe mmolecule
Shape mof mthe mmolecule
,Nucleotide msequence mof mthe mmolecule m- mcorrect manswer.Nucleotide msequence mof mthe
mmolecule
What mare mthe mphases min ma mqPCR mAmplification mPlot?
Initiation, mexponential, mplateau
Baseline, mexponential, mplateau
Baseline, mthreshold, mexponential, mplateau
Baseline, minitiation, mthreshold, mexponential, mplateau m- mcorrect manswer.Initiation,
mexponential, mplateau
Find mthe mpalindrome min mthis mrestriction menzyme msite: m5'-CTGCAG-3'?
5'-GAC
3'-GAC
3'-CTG
5'-GTC m- mcorrect manswer.3'-GAC
A mpatient mwith mimpaired mjudgment, mpersonality mchanges, msigns mof mabnormal mbody
mmovements mand mdepression mcomes mto mthe mphysician's moffice mfor ma mfollow-up mvisit.
mThe mphysician msuspects ma msingle-gene mdisorder mmay mbe mthe mcause mof mthose mclinical
mmanifestations. mA mblood mspecimen mwas mthen msent mto myour mclinical mlaboratory mfor
mmutation mscreening min mthe mHuntington mgene. mTesting mwith mstandard mPCR mindicates
mthat mpatient mhas mHuntington mDisease, mHD. mWhich mof mthe mfollowing mwould mbe
mconsistent mwith mthis mdiagnosis?
25 mCAG mrepeats min mthe mHuntington mgene
85 mCAG mrepeats min mthe mHuntington mgene
25 mCGA mrepeats min mthe mHuntington mgene
85 mCGA mrepeats min mthe mHuntington mgene m- mcorrect manswer.85 mCAG mrepeats min mthe
mHuntington mgene
Which mtwo mHPV mtypes mare mresponsible mfor mmost mcases mof mcervical mcancer?
16 mand m18
31 mand m59
16 mand m58
44 mand m59 m- mcorrect manswer.16 mand m18
Replication mforks, mknown mas morigins mof mDNA mreplication, mare mcreated mby mthis menzyme:
Ligase
Taq mPolymerase
Primase
Helicase m- mcorrect manswer.Helicase
Mutation min mwhat mgene mis massociated mwith mFragile mX msyndrome? m- mcorrect
manswer.FMR1
, Mantle mcell mlymphoma m(MCL) mis mcaused mby mwhat mtranslocation? m- mcorrect
manswer.t(11;14)
This mpolymerase mis minvolved min m"initiation mof mDNA mreplication mand mhas mprimase
mactivity": m- mcorrect manswer.Pol mα
Its mdiscovery mshed mlight mon mwhy mthere mis msimultaneous, mthough mnot mcontinuous,
msynthesis mof mDNA mon mboth mleading mand mlagging mstrands mof mDNA:
Klenow mfragment mof mDNA mpolymerase
Okazaki mfragments
Sanger mfragments
RNA mfragments m- mcorrect manswer.Okazaki mfragments
What mgene mis mmeasured mfollowing mtreatment mwith mimatinib m(Gleevec)?
FLT3
BCR/Abl
Jak2
MAPK m- mcorrect manswer.BCR/Abl
What mis mthe mrate mof mmammalian mDNA mreplication?
500 mnucleotides mper msecond
100 mnucleotides mper msecond
50 mnucleotides mper msecond
10 mnucleotides mper msecond m- mcorrect manswer.50 mnucleotides mper msecond
This mpolymerase mis minvolved min m"replicates mmitochondrial mDNA": m- mcorrect manswer.Pol
mγ
A mpatient mwith mimpaired mjudgment, mpersonality mchanges, msigns mof mabnormal mbody
mmovements mand mdepression mcomes mto mthe mphysician's moffice mfor ma mfollow-up mvisit.
mThe mphysician msuspects ma msingle-gene mdisorder mmay mbe mthe mcause mof mthose mclinical
mmanifestations. mA mblood mspecimen mwas mthen msent mto myour mclinical mlaboratory mfor
mmutation mscreening min mthe mHuntingtin mgene. mWhich mof mthese mmethods mwould mbest
maccomplish mthis mtask?
Methylation-specific mPCR
Standard mPCR
PFGE
RAPD mPCR m- mcorrect manswer.Standard mPCR
Which mof mthe mfollowing mstorage moptions mis moptimal mfor mstoring misolated mDNA mfor ma
mperiod mgreater mthan mseven myears?
22-25ºC
2-8ºC
-20ºC
-70ºC m- mcorrect manswer.-70ºC
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