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USMLE Step 3: Rheumatology Exam Prep Questions And Answers ()
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USMLE Practice Exam Exam Prep Questions And Answers (202472025)Cause of ARDS on a histological level? - ✔✔Injury and inflam of alveolar
pneumoncytes and pulmonary endothelium from neutrophils
Glomerular biopsy shows mesangial expansion, glomerular BM thickening,
glomerular sclerosis. If sclerosis is nodular and large it is a Kimmelstiel-Wilson
lesion(hyaline deposits)? - ✔✔Long standing Diabetes
Right hip radiograph shows mixed lysis and sclerosis with focal periosteal elevation
and reactive new bone formation? - ✔✔Osteosarcoma
Right hip radiograph shows crescent sign and subchondral collapse? - ✔✔Avascular
necrosis of hip
Right hip radiograph shows generalized osteosclerosis and evidence of fractures? -
✔✔Osteopetrosis
What is globus sensation(globus hystericus, globus pharyngeus)? - ✔✔Abnormal
sensation of a foreign body, tightness, or fullness in the throat. Worse with
swallowing saliva. A functional disorder
Pt presents with feeling like something is stuck in her throat. She has more difficulty
swallowing saliva. Upper GI shows no abnormality. No neck abnormality? -
✔✔Globus sensation Functional disorder
What is Pseudobulbar palsy? - ✔✔Neurological condition caused by MS which
results in dysarthria, dysphagia, dysphonia, and impaired movement of the tongue
and facial muscles
,What vitamin can be teratogenic in pregnancy? - ✔✔Vitamin A(fetal microcephaly,
cardiac anomalies, early epiphysial closure, growth retardation, or spontaneous
abortion)
DNA electrophoresis reveals fragmentation in multiples of 180 bases what does this
indicate? - ✔✔Laddering of DNA and is fairly specific from apoptosis from
endonucleases that cleave DNA at internucleosomal linker regions
Atropine muscarinic effects? - ✔✔Muscarinic antagonist
Pt begins acting bizarre after chewing plant seeds. Says bugs are crawling on him,
talking to people who arent there, has trouble seeing, continues to ask for drinking
water? What drug overdose? - ✔✔Jimson weed or Atropine(Anticholinergic excess
- hot as a hare, dry as a bone, red as a beet, blind as a bat, and mad as a hatter)
Family has two children with osteogenesis imperfecta but no family history of
disease? what should be suspected? - ✔✔Germline mosaism. Chance of next child
will be determined by ratio of wild type to germline mutated gametes
How often should foot inspections and pinprick sensation testing be done on
diabetes? - ✔✔Foot: Daily and Pinprick: Yearly
t(12:21)? - ✔✔Childhood B cell acute lymphocytic leukemia
What IL is produced exclusively by lymphocytes? - ✔✔IL-2
What cell cell adhesion molecules are calcium dependent and join cell together
rather than too the BM? - ✔✔Cadherins
, What two intercellular adhesions utilize cadherins? - ✔✔Desmosomes and adherens
junctions
What artery can be damaged by posterior dislocation of the tibia relative to the
femur? - ✔✔Popliteal artery because it is held in place rigidly by the adductor
magnus and soleus muscle
Pt recently gave birth and uterus is found to be tender and there is a foul smelling
discharge? What organism?` - ✔✔Endometritis from Bacteroides species that
normally colonize the uterus
What mature defense mechanism results from channeling impulses into socially
acceptable behaviors? - ✔✔Sublimation
What defense results from responding in a manner opposite to one's actual feelings?
- ✔✔reaction formation
What defense mechanism results from transferring feelings to a more acceptable
object? - ✔✔Displacement
What is nasal vestibulitis? - ✔✔Infection with staph of the internal nares with
mucosal edema and nasal congestion
What happens to the GFR in a pt with nephrectomy in 4-6 weeks? - ✔✔GFR returns
to 80% of previous value
What is the job of the corpus spongiosum? - ✔✔Maintain patency of urethra during
ejaculation
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