Pancreas Histology Review Practice Test.
Structure and function of the exocrine pancreas:
• Pancreatic acinar cells
• Zymogen granules (and other intracellular structures)
• Centroacinar cells
• Duct system (Intercalated duct---Intralobular duct----Interlobular duct--- Pancreatic d...
• Zymogen granules (and other intracellular structures)
• Centroacinar cells
• Duct system (Intercalated duct---Intralobular duct----Interlobular duct--- Pancreatic duct) - CORRECT
ANSWER What cells can be found in A?
Structure and function of the endocrine pancreas
• Hormones produced by the islets of Langerhans (Insulin, glucagon, somatostatin and pancreatic
polypeptide)
•Hormones secreted by each different cell types (b-,a-,d-,andPP-cells) - CORRECT ANSWER What is the
structure and function of the structure with blue arrows?
Dual blood supply: Acinar and insuloacinar vascular system - CORRECT ANSWER What is the blood
supply of the pancreas?
Its exocrine function is the production of digestive enzymes that are carried via the pancreatic duct to
the duodenum. - CORRECT ANSWER What is the exocrine function of the pancreas?
Its endocrine function involves the release of hormones that regulate carbohydrate metabolism. The
endocrine portion of pancreas, islets of Langerhans, are scattered among the exocrine portion (secretory
acini).
Its flimsy connective tissue capsule forms septa, which subdivide the gland into lobules. - CORRECT
ANSWER What is the endocrine function of the pancreas?
The pancreas develops from two outgrowths of the foregut.
, **The ventral diverticulum gives rise to the common bile duct, gallbladder, liver and the ventral
pancreatic anlage that becomes a portion of the head of the pancreas with its duct system including the
uncinate portion of the pancreas.**
**The dorsal pancreatic anlage gives rise to a portion of the head, the body, and tail of the pancreas
including a major duct.** - CORRECT ANSWER How does the pancreas develop (from embryology)?
What does its embryologic parts develop into?
Fusion of the duct systems results in the formation of the main pancreatic duct from the ducts of both
dorsal and ventral anlagen. The caudal portion of the head of the pancreas (uncinate) and the major
papilla (ampulla of Vater) are derived from the ventral anlage. The minor papilla is derived from the
dorsal anlage. - CORRECT ANSWER pancreas embryology
This tissue section illustrates developing exocrine tissue in the center (arrows) surrounded by primitive
mesenchymal and hematpoietic cells at an estimated gestational age of 5 weeks.
The pancreatic tissue is composed of a network of interconnecting (anastomosing) tubules. - CORRECT
ANSWER Where can the developing exocrine tissue be found at? What is the surrounding area (outside
of the yellow arrows)? What is the developing pancreatic tissue composed of?
Centroacinar cells are typically located at **the junction of an acinus or acinar tubule with a small
ductile**.
In this drawing many acinar cells have been replaced by duct cells. - CORRECT ANSWER Where are
centroacinar cells located in the fetal pancreas?
This process, called acinar to ductal metaplasia (ADM), occurs in chronic pancreatitis. - CORRECT
ANSWER What is the cell change in chronic pancreatitis?
It is composed of tubuloacinar gland that produces daily about 1200 ml of a bicarbonate-rich fluid
containing digestive proenzymes and enzymes.
40-50 acinar cells form a round to oval acinus. The lumen of the acinus is occupied by 3 or 4
centroacinar cells, which form the beginning of the duct system.
The presence of centroacinar cells in the center of the acinus is a distinguishing characteristic of this
gland. - CORRECT ANSWER What is the exocrine pancreas composed of? What does it produce?`
(A) Centroacinar cells are terminal end duct cells that interface with acini
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