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HMX Pharmacology Quiz – Questions With Solutions
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HMX Pharmacology Quiz – Questions With Solutions
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HMX Pharmacology Quiz – Questions With SolutionsToxicity cause by binding of drug to its intended receptor in unintended tissue
is an examle of ____ drug toxicity? Right Ans - on target
The classical small molecule drugs and the newer therapeutics, such as
biologics, differ in many ways. The defining difference between these drug
modalities is their Right Ans - molecular weight
A monoclonal antibody is an example of a Right Ans - protein based
therapy
The ____________ index of a drug indicates the margin of safety of the drug.
Right Ans - therapeutic
If the elimination rate of a drug does not increase when the concentration of
the drug in the plasma increases, this drug most likely follows ____________.
Right Ans - zero-order kinetics
Calculating the therapeutic dose of a drug involves a determination of the
____________ of the drug Right Ans - ED50
The goals of ____________ clinical trials are to determine the efficacy and
tolerability of an investigational drug, often in comparison to a standard of
care medication for the condition of interest. Right Ans - phase III
When determining the bioavailability of a drug administered by a given route,
if a ____________ fraction of drug reaches the ____________, then the bioavailability,
expressed as a percentage, will be low.
small; systemic circulation
large; systemic circulation
small; portal circulation
large; portal circulation Right Ans - small; systemic circulation
Which of the following types of drugs will decrease the basal activity of a
receptor? Right Ans - inverse agonist
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