NURS 5334 ADV. PHARMACOTHERAPEUTICS FINAL
REVIEW EXAM
Why don't many drugs provide pediatric dose information on their drug labels?
A. Most drugs are not used in children.
B. There is insufficient evidence-based literature on the safe and effective use of
drugs in children.
C. The FDA prohibits pediatric dosage information on product labels.
D. Only medications accessible in oral liquid formulations are required to include
pediatric dose information on their labels. - ANSWER B. There is insufficient
evidence-based literature on the safe and effective use of drugs in children.
Why do neonates have a higher risk of toxicity with highly protein-bound drugs?
A. In neonates, protein binding decreases, increasing the amount of free drug
accessible.
B. Protein-bound medicines are not properly removed in newborns.
C. These highly protein-bound pharmaceuticals cannot be metabolized by neonates.
D. Protein binding is increased in newborns, resulting in incorrect drug serum level
measurements. - ANSWER A. In neonates, protein binding decreases, increasing
the amount of free drug accessible.
At what age does adult renal function reach its peak?
A. Six months.
B: 12 months
C: 24 months
,D. Three years old - ANSWER B: Twelve months
What is the list of pharmaceuticals that are highly likely to cause harmful effects in
the elderly?
A. No-use list
B. Beer list.
C. Pharmacist's list
D. Adverse Drug List - ANSWER B. Beer List
In pediatric patients, stomach acidity does not reach adult levels for ______ -
ANSWER 2 years.
The following principles underpin drug therapy complications in the elderly: ___,
____, ____, and ____. - ANSWER: changed pharmacokinetics, multiple and severe
diseases, multidrug therapy, and poor adherence.
Altered medication absorption in the elderly may result in ____ drug ANSWER. -
Answer Delay
The four key factors that can affect drug distribution in the elderly are: _, _, _, and
_? - ANSWER: increased body fat, decreased proportion of lean body mass,
decreased total body water, and lower serum albumin concentration.
The most common cause of adverse medication ANSWERs in the elderly is drug
buildup due to decreased renal elimination.
The correct renal function index for the elderly is____. - Answer: creatinine
clearance or GFR.
, Factors contributing to the rise in adverse ANSWERs among the elderly include: -
ANSWER • Polypharmacy
• Severe sickness.
• Multiple pathologies,
• increased use of medications with a low therapeutic index.
• Insufficient supervision.
• Poor patient adherence.
What is the highest dose of Sumatriptan that can be taken in one day?
A. 100 mg
B. 200 mg
C. 300 mg
D. 400 mg, ANSWER B. 200 mg
The anesthetic's capacity to enter the axon membrane is determined by three
features. What are they?
A. Molecular Size
B. Protein Binding Potential
C. Lipid solubility.
D. Degree of Ionization at Tissue pH
E. Water solubility.
F. Degree of Blood Flow - Answer A. Molecular Size
C. Lipid solubility.
REVIEW EXAM
Why don't many drugs provide pediatric dose information on their drug labels?
A. Most drugs are not used in children.
B. There is insufficient evidence-based literature on the safe and effective use of
drugs in children.
C. The FDA prohibits pediatric dosage information on product labels.
D. Only medications accessible in oral liquid formulations are required to include
pediatric dose information on their labels. - ANSWER B. There is insufficient
evidence-based literature on the safe and effective use of drugs in children.
Why do neonates have a higher risk of toxicity with highly protein-bound drugs?
A. In neonates, protein binding decreases, increasing the amount of free drug
accessible.
B. Protein-bound medicines are not properly removed in newborns.
C. These highly protein-bound pharmaceuticals cannot be metabolized by neonates.
D. Protein binding is increased in newborns, resulting in incorrect drug serum level
measurements. - ANSWER A. In neonates, protein binding decreases, increasing
the amount of free drug accessible.
At what age does adult renal function reach its peak?
A. Six months.
B: 12 months
C: 24 months
,D. Three years old - ANSWER B: Twelve months
What is the list of pharmaceuticals that are highly likely to cause harmful effects in
the elderly?
A. No-use list
B. Beer list.
C. Pharmacist's list
D. Adverse Drug List - ANSWER B. Beer List
In pediatric patients, stomach acidity does not reach adult levels for ______ -
ANSWER 2 years.
The following principles underpin drug therapy complications in the elderly: ___,
____, ____, and ____. - ANSWER: changed pharmacokinetics, multiple and severe
diseases, multidrug therapy, and poor adherence.
Altered medication absorption in the elderly may result in ____ drug ANSWER. -
Answer Delay
The four key factors that can affect drug distribution in the elderly are: _, _, _, and
_? - ANSWER: increased body fat, decreased proportion of lean body mass,
decreased total body water, and lower serum albumin concentration.
The most common cause of adverse medication ANSWERs in the elderly is drug
buildup due to decreased renal elimination.
The correct renal function index for the elderly is____. - Answer: creatinine
clearance or GFR.
, Factors contributing to the rise in adverse ANSWERs among the elderly include: -
ANSWER • Polypharmacy
• Severe sickness.
• Multiple pathologies,
• increased use of medications with a low therapeutic index.
• Insufficient supervision.
• Poor patient adherence.
What is the highest dose of Sumatriptan that can be taken in one day?
A. 100 mg
B. 200 mg
C. 300 mg
D. 400 mg, ANSWER B. 200 mg
The anesthetic's capacity to enter the axon membrane is determined by three
features. What are they?
A. Molecular Size
B. Protein Binding Potential
C. Lipid solubility.
D. Degree of Ionization at Tissue pH
E. Water solubility.
F. Degree of Blood Flow - Answer A. Molecular Size
C. Lipid solubility.
