What are the two theories of cancer? - answer Genetic & Epigenetic
Which theory states that the formation and development of a tumor results from
changes in DNA? - answer Genetic Theory
In regards to the genetic theory, are the mutations that occur in DNA permanent? -
answer Yes
Which theory states tumors result from alterations of RNA and proteins? - answer
Epigenetic Theory
Which is not an epigenetic mechanism for modifications?
A. DNA methylation
B. Mutations
C. Histone post-translation modification
D. Alteration of microRNA – answer B. Mutations
______ agents are responsible for the addition of DNA (genetic theory).
A. Chemical
B. Biological
C. Physical
D. All of the above – answer B. Biological
Which two agents are always responsible for mutations? - answer Chemical and
Physical
In regards to the Genetic theory, mutations include all but the following.
A. Insertion
B. Addition
C. Alteration
D. Deletion - answerB. Addition
True or False: The DNA of the original cell is not permanently changed and will not be
transmitted to the daughter cells. - answerFalse
______ of DNA is the integration of genetic material into the cell's DNA and can be
caused by infection by oncogenic viruses.
, A. Insertion
B. Addition
C. Alteration
D. Subtraction - answerB. Addition
T/F: All mutations lead to cancer. - answerFalse
T/F: Epigenetic modifications cannot be reversed. - answerFalse; They can be reversed
In regards to the Epigenetic theory, does the DNA stay intact? - answerYes
Hypermethylation of CpG islands would lead to _______. - answerPrevention of gene
expression
Hypomethylation of promoters of protoncogenes would lead to __________. -
answerCancer formation (activation of proto oncogene.
T/F: Cell-to-cell contact will not control mitosis (cell proliferation). - answerFalse
_____ is another name for cancer cells. - answerAtypical
T/F: If a cells morphology has changed , then its function has not changed. -
answerFalse; function has changed also
Less differentiation =
A. More aggressive
B. Less aggressive - answerA. More aggressive
T/F: Mitosis and Differentiation are inversely related. - answerTrue
_____ cells have uncontrolled mitosis and less differentiation.
A. Cancerous
B. Normal - answerA. Cancerous
_____ cells have controlled mitosis and have morphologically and physiologically
different cell types.
A. Cancerous
B. Normal - answerB. Normal
T/F: Cancer cells have small non-variably shaped nuclei. - answerF: Cancer cells have
large, variably shaped nuclei
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