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Test Bank for Becker's world of the cell Ch 24 (10th Edition by Jeff Hardin)
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Test Bank for Becker's world of the cell Ch 24 (10th Edition by Jeff Hardin)
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Test Bank for Becker's world of the cellCh 24 (10th Edition by Jeff Hardin)
spindle assembly checkpoint - ANSOperates at the metaphase/anaphase transition to check for
misaligned chromosomes (the third critical checkpoint).
Control of the cell cycle must - ANS1. Ensure that events of each phase are carried out in the
correct order and at the appropriate time
2. Ensure that each phase is completed before the next one begins
3.Respond to external conditions
3. Respond to external conditions
restriction point/control point - ANS1st transition point: A point of no return in the cell cycle; once
this point passes, a cell is committed to S phase, ability to pass this is influenced by
extracellular growth factors. those that do not, enter into G0 and reside there until a signal
allows them to reenter G1 and pass through the remaining restriction points
G2-M transition - ANS2nd transition point where the commitment is made to enter mitosis.
In some cell types, the cell can be arrested in G2 indefinitely and the cell enters a state
analogous to G0, such as frog eggs
Transition point during M phase - ANS3rd transition point :all the chromosomes must be
properly attached to the spindle before moving into anaphase, this phase is between metaphase
and anaphase, commitment is made to move the two sets of chromosomes into the new cells
heterokaryon - ANSform a cell with two nuclei
What do the experiments with fusion of Sphase cells and G1 cells suggest? - ANSThese
experiments suggest that molecules in the cytoplasm drive cells from G1 to S or G2 to M
cdc2 - ANSencodes a protein kinase, , whose activity is needed for the G2 to M transition
cyclin-dependent kinases (Cdks) - ANSa regulatory protein that depends upon the presence of
cyclin to complete its function, also the phosphorylation of Cdks helps regulation of transition
points.
MPF - ANSpromotes the entrance into mitosis (the M phase) from the G2 phase by
phosphorylating multiple proteins needed during mitosis.
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