HMX LYMPHOCYTE DEVELOPMENT AND DIVERSITY; Questions & Answers 100% Pass
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Course
HMX Pharmacology
Institution
HMX Pharmacology
HMX LYMPHOCYTE DEVELOPMENT AND
DIVERSITY; Questions & Answers 100% Pass
Which of the following is an accurate statement about antibody recognition of antigen?
Answer-Antibodies can recognize any class of molecule outside of cells.
The adaptive immune system is responsible for coordinating a ...
HMX LYMPHOCYTE DEVELOPMENT AND
DIVERSITY; Questions & Answers 100% Pass
Which of the following is an accurate statement about antibody recognition of antigen?
Answer-Antibodies can recognize any class of molecule outside of cells.
The adaptive immune system is responsible for coordinating a specific response to microbes, in
contrast to the innate immune system, which provides a rapid, but generalized, response.
Which of the following is NOT a challenge that the adaptive immune system must overcome to
mount a specific response to a microbe? Answer-Lymphocyte receptors are not
sufficiently diverse to recognize all possible microbes.
Expansion Answer-Clonal selection describes the interaction between microbial antigen
and its specific lymphocyte receptor, while clonal ____________ describes the proliferation of
the lymphocyte in response to the antigen-receptor interaction.
Which of the cells, below, arise from the common lymphoid progenitor (CLP)? Answer-NK
cells,B cells
stem cell Answer-A cell that can undergo self-renewal and differentiate into any of the
cells of the blood is called a hematopoietic ____________.
Granulocytes Answer-Neutrophils, eosinophils, and basophils are all examples of
____________, which are cells that have many granules in their cytoplasm.
, HMX LYMPHOCYTE DEVELOPMENT AND
DIVERSITY; Questions & Answers 100% Pass
bone marrow Answer-Consider the anatomical locations of blood cell development. The
earliest stages of HSC differentiation occur in the ____________.
At a certain stage in B cell development, the developing B cells move to lymphoid tissues. This
occurs at which stage of differentiation? Answer-immature B cell
At which stage of development do B cells first express immunoglobulin (Ig) heavy chains?
Answer-pre-B cell
thymus Answer-At the pro-T cell stage, differentiating T cells migrate to the
____________, the site of all subsequent stages of T cell development.
What structure binds to the T cell receptor? Answer-a peptide bound to an MHC protein
Cytotoxic T cells (CTLs) are a subset of T cells that express the molecule CD8 on their cell surface
and contain granules filled with proteins that can cause death to infected cells. In the right
circumstances, when they bind to antigen they will release these granule contents as a "lethal
payload." The granule contents induce apoptosis in the cell that displays the antigen.
What type of pathogen cannot be controlled by CTLs? Answer-bacteria that replicate
outside of cells
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