MH701 Frontier
exam(111
questions fully
solved)
What is pharmacodynamics? - answer What
the drug does to the body
What is pharmacokinetics - answer What the
body does to the drug (absorption,
distribution, metabolism, excretion)
Psychotropic medications - answer
medications used to treat psychiatric
disorders
What is pharmacogenetics - answer Explains
how genetic variation leads to altered drug
,responses in different individuals and ethnic
groups
What is drug toxicity? - answer The degree
to which a drug can be poisonous or harmful.
it occurs when too much of the drug is
accumulated in the bloodstream. (CYP450
system determines this)
What is steady state? - answer Condition in
which the rate of absorption equals the rate
of elimination. It is acheived in 4-5 half-lives.
What is drug half-life? - answer The time
required for the amount of drug in the body
to decrease by 50%
Classes of psychotropic drugs - answer
Antidepressants
Antipsychotics
Mood stabilizers
Anxiolytics
Hypnotics
Cognitive enhancers, and Stimulants
,Agonist - answer A chemical that mimics the
action of a neurotransmitter. A drug or
medication that binds to a specific receptor
producing an effect identical to that usually
produced by the neurotransmitter affecting
that receptor.
Antagonist - answer A compound that binds
to a receptor that blocks or reduces the
action of another substance (agonist) at the
receptor site involved.
Antagonists that compete with an agonist for
a receptor are competitive antagonists.
Those that antagonize by other means are
noncompetitive antagonists
Partial Agonist - answer Medication that
produces a weaker, or less efficacious,
response than an agonist.
A compound that (even when fully occupying
a receptor) possesses affinity for a receptor,
but elicits a partial pharmacological response
at the receptor involved.
, Inverse Agonist - answer Chemical substance
that produces effects opposite those of a
particular neurotransmitter
What is the significance of understanding
about CYP 450 when prescribing various
medications that may affect this? - answer
Inducers-speed up other drugs' metabolism
Which equals leaving the body quicker
Which equal little to no effect intended
effect.
Inhibitors- block the enzyme so decreases
the body's ability to use drug
Which leaves too much circulating drug
What medications will most be affected by
CYP 450? - answer Inducers
Mnemonic- CRAPGPS
Cabamazepine
Rifampin
Alcholol
Phenytion
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