Reading guide for chapter 5 of Human Anatomy (9th Edition), by Marieb et al: "Integument". Used in the Applied Human Anatomy course at UC Irvine. Comes with bolded text answers and colored diagrams you can label.
What are the five functions of the skin (integument)?
1. Protection. Epidermis is waterproof -> prevents water loss. Produces a layer of pigment that
protects against UV radiation.
2. Thermoregulation. The skin’s capillaries and sweat glands regulate heat loss.
3. Excretion. Skin excretes sweat: urea, salts, and water.
4. Production of vitamin D. Epidermal cells + UV radiation = vitamin D (absorbs calcium).
5. Sensory reception. Skin contains sensory receptors that are associated w/ nerve endings.
The Epidermis: Describe the basics of each layer, using the appropriate key words.
● Stratum basale: The deepest epidermal layer, attached to the underlying dermis.
Consists of a single row of mitotically-active stem cells, which become keratinocytes.
○ Among them are tactile epithelial cells, which act as touch receptors. Encompass
sensory nerve endings.
○ 10-25% of cells are melanocytes. Transfer melanin granules to nearby keratinocytes. -
> Shield cell nuclei from UV rays.
○ Light-skinned people have lysosomes that digest melanin in cells above the stratum.
○ Dark-skinned people have darker melanin, more granules, and more pigment in each
melanocyte.
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