GMS6551: Pharmacogenetics Questions With Complete
Solutions
A physician walks into a patient room and can immediately
draw conclusions regarding which one of the following sources
of individuality in terms of drug response? Correct Answers ......
Condition or state of being
......
At which age would you expect a patient to have the highest
levels of P450 activity? Correct Answers 50 years (middle aged)
...... .... ..
Prilosec is a substrate for P450 enzymes. Ingesting which of the
following would likely increase its metabolism? Correct ......
Genetics can influence which of the following? Correct Answers ......
Pharmacokinetics AND pharmacodynamics
......
Giving the same dose of isoniazid to two patients, if one is a
rapid acetylator and one is a slow acetylator, the slow acetylator
will have ______ isoniazid in their blood one hour following
dosing. Correct Answers More
...... .... ..
Using any resource, which of the following has an adverse drug
interaction with Xanax? Correct Answers Indinavir
...... .... ..
Which of the following could happen in a single SNP exists?
-A truncated drug metabolizing enzyme
- Gene amplification (too many copies) of the EGFR in breast
cancer
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