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ONCC-BMTCN Latest Test Guide (Q & S) - All Subject Areas - 2024 $12.49   Add to cart

Exam (elaborations)

ONCC-BMTCN Latest Test Guide (Q & S) - All Subject Areas - 2024

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  • August 12, 2024
  • 27
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • ONCC
  • ONCC
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ONCC-BMTCN



All Subject Areas

LATEST TEST GUIDE (Q & S)



2024

,Q: What is the primary indication for allogeneic stem cell transplantation in
hematologic malignancies?

A) To replace diseased bone marrow
B) To provide a graft-versus-tumor effect

C) To facilitate high-dose chemotherapy
D) To support gene therapy procedures

Correct Answer: B) To provide a graft-versus-tumor effect

Rationale: Allogeneic stem cell transplantation is primarily indicated to
exploit the graft-versus-tumor effect, where donor immune cells attack any
residual malignant cells, providing a therapeutic benefit.



Q: Which source of hematopoietic stem cells is typically associated with the
fastest engraftment?

A) Bone marrow
B) Peripheral blood

C) Umbilical cord blood

D) Adipose tissue

Correct Answer: B) Peripheral blood
Rationale: Peripheral blood stem cells are associated with faster engraftment
compared to bone marrow or umbilical cord blood due to the higher
number of stem cells collected.



Q: What is the most critical factor to assess before proceeding with a
hematopoietic stem cell transplant?

, A) Donor-recipient compatibility

B) Patient's psychological readiness

C) Availability of post-transplant care

D) Insurance coverage

Correct Answer: A) Donor-recipient compatibility

Rationale: Ensuring donor-recipient HLA compatibility is crucial to reduce
the risk of graft-versus-host disease and ensure the best possible outcome
for the transplant.



Q: What is the purpose of administering a conditioning regimen before
stem cell infusion?

A) To stimulate stem cell proliferation

B) To suppress the immune system

C) To eradicate residual disease

D) To promote stem cell homing

Correct Answer: C) To eradicate residual disease
Rationale: The conditioning regimen, which may include chemotherapy
and/or radiation, is designed to eradicate the patient's residual disease and
suppress the immune system to prevent rejection of the graft.



Q: Which medication is commonly used for the prophylaxis of acute
GVHD?
A) Cyclosporine

B) G-CSF

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