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Lehne-s Pharmacology CH 27 questions with answers
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Lehne-s Pharmacology CH 27 questions with answers
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Lehne's Pharmacology CH 27 questions withanswers
are drugs that produce unconsciousness and a lack of responsiveness to all painful stimuli
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Given only by licensed anesthesiologists (physicians) and certified registered nurse
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anesthetists
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Used to facilitate certain procedures - ANSWER: ➡ General anesthetics
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Molecular mechanism of action of Inhalation Anesthetics - ANSWER: ➡ Enhances
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transmission at inhibitory synapses
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Depresses transmission at excitatory synapses
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Except for nitrous oxide, all of the agents used today enhance the activation of receptors for
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gamma-aminobutyric acid, which is the principal inhibitory transmitter in the central
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nervous system (CNS)
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Minimum alveolar concentration - ANSWER: ➡ The minimum concentration of drug in the
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alveolar air that will produce immobility in 50% of patients exposed to a painful stimulus
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Drug Interactions of General Anesthetics - ANSWER: ➡ Analgesics, CNS depressants, and
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CNS stimulants can influence the amount of anesthetic required to produce anesthesia
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Opioids allow for a reduction
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CNS depressants add to the depressant effects of anesthesia
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, Given to reduce anxiety, produce perioperative amnesia, and relieve preoperative and
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postoperative pain - ANSWER: ➡ Preanesthetic medications
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What do surgical procedures require? - ANSWER: ➡ skeletal muscle relaxation
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reduce amount of anesthesia needed and prevent contraction of all skeletal muscles,
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including diaphragm and muscles of respiration (flaccid paralysis) - ANSWER: ➡
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Neuromuscular blocking agents
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Examples of Postanesthetic Medications - ANSWER: ➡ Analgesics
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Antiemetics
Muscarinic antagonists m
Halothane
Enflurane
Desflurane
Sevoflurane
Nitrous oxide m
Obsolete inhalation anesthetics
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Anesthetic Properties of Halothane - ANSWER: ➡ High-potency anesthetic
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Time course: Smooth and relatively rapid
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Weak analgesia
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Muscle relaxation generally inadequate for surgery
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Adverse Effects of Halothane - ANSWER: ➡ Hypotension
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Respiratory depression m
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