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GMS 6540 Homework Questions With Complete Solutions
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GMS 6540 Homework Questions With Complete Solutions
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GMS 6540 Homework Questions With Complete SolutionsGenetic changes are required for which of the following to
occur? Select all that apply. Correct Answers ......
Initiation/Transformation of a cell
......
Formation of a malignant tumor from a pre-neoplastic lesion
Formation of clinical cancer from a malignant tumor
Metastasis of a clinical cancer
What effect would a G12V mutation in Ras have on ERK?
Correct Answers It would lead to increased activation of ERK
...... ......
Are cancers more likely to develop mutation that activate or
inactivate Rb? Correct Answers Inactivate
...... ......
Metabolites of nicotine commonly result in DNA point
mutations. Which type of DNA instability is this an example of?
Correct Answers Genetic instability
...... ......
If a human cell underwent endoreduplication followed by failed
cytokinesis, how many chromosomes would you expect that cell
to now contain? Correct Answers 184
...... ... ...
Which of the following statements is true regarding apoptosis.
Correct Answers Cancer cells must avoid it
...... ......
Which statement best describes the Warburg effect? Correct ......
Answers The switching of cancer cells from oxidative
.... ..
phosphorylation to aerobic glycolysis
, A patient undergoes an FdG-PET scan. Will a tumor contain
more or less 18fluorodeoxyglucose than normal the surrounding
tissue? Correct Answers More
...... ......
Angiogenesis is __________________. Correct Answers the ...... .... ..
process of creating new blood vessels from current blood vessels
Is inflammation harmful or beneficial to cancer? Correct ......
Answers Beneficial .... ..
If a cell expresses a mutant form of EGFR, would this be
considered a tumor specific antigen or a tumor associated
antigen? Correct Answers Tumor specific antigen
...... .... ..
Which statement best describes how cancer cells overcome the
Hayflick limit? Correct Answers They upregulate telomerase
...... ... ...
What chemical causes the most cigarette-related DNA
mutations? Correct Answers Benzo[a]pyrene ...... ......
The Epstein-Barr virus, most famous for causing
mononucleosis, also plays a prevalent role in the formation of
what type of cancer? Correct Answers Burkitt's lymphoma ...... ......
What viral protein is capable of inhibiting p53? Correct Answers ......
E6
......
Which class of cancer drugs is the least selective towards cancer
cells? Correct Answers Chemotherapy
...... ......
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