,BCPS 2024 exam review questions and
answers
1. age 80 or older
2. weight 60 kg or less
3. SCr 1.5 or greater
When to dose reduce rivaroxaban and edoxaban for renal function? - CrCl < 50
Rivaroxaban to 15 mg daily and edoxaban to 30 mg daily
When to dose reduce dabigatran for renal function? - CrCl < 30 to 74 mg BID
Protamine is a reversal agent for: - Heparin
Off label: LMWH
Andexanet alfa is a reversal agent for: - Factor Xa inhibitors (apixaban &
rivaroxaban)
Idarucizumab (Praxbind) is the reversal agent for: - Dabigatran
INR goal for mechanical mitral valve - 2.5-3.5
,BCPS 2024 exam review questions and
answers
Duration of treatment with aspirin for patients with bioprosthetic surgical aortic
or mitral valves - indefinitely
Duration of treatment with DAPT for patients with bare metal stent - at least 1
month
Duration of treatment with warfarin for patients with bioprosthetic surgical aortic
or mitral valves - at least 3 months
Duration of treatment with DAPT for patients with a drug-eluting stent - at least 1
year
Risk factors for developing VTE - Age > or = 40
Surgery
Trauma
Hypercoagulable states
Central venous catheterization
Estrogen use or selective estrogen receptor modulators
, BCPS 2024 exam review questions and
answers
Erythropoiesis-stimulating agents
Previous VTE
Cancer & treatments
Immobility or lower-extremity paresis
Various medical conditions/disease states
Smoking
Obesity
VTE treatment strategies - Bridging -- Injectable + warfarin w/ at least 5 days
overlap or until INR > 2
Switching -- Injectable x 5 days then start edoxaban or dabigatran
Monotherapy -- apixaban or rivaroxaban at high dose then lower maintenance
Dabigatran dosing for VTE treatment - 150 mg BID after 5-10 days of injectable
Rivaroxaban dosing for VTE treatment - 15 mg BID w/ food x 21 days then 20 mg
daily w/ food
after 6 months, may be reduced to 10 mg daily
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