what is bioavailability - ANSWERthe percentage thats left for body to use
, what does first pass only effect - ANSWERoral and GI
factors of bioavailabilty - ANSWERabsorption, first pass effect, drug form, route of
administration, gastric mucosa and mobility, admin with food, change in liver
metabolism
drug distribution is what - ANSWERonce the drug leaves the GI tract
drug distribution involves what - ANSWERmovement of drug from circulation to body
tissue, protein binding, and free drugs
protein binding percentage used - ANSWER40% to protein 60% used to body
drug metabolism (biotransformation) is what - ANSWERprocess of body chemically
changing a drug into a form to be excreted, uses half life and loading dose
half life is what - ANSWERtime it takes for amount of drug in body to be reduced by half
loading dose is what - ANSWERa higher dose given at the beginning of treatment
drug excretion (elimination) - ANSWERfrom the kidneys, creatinene clearance, BUN
levels, glomerular filtration rate. from the liver the bile, LFT test for liver function, feces,
lungs, saliva, sweat, breast milk
the tip of eye medicine should never what - ANSWERtouch the conjunctiva sack
what do you need to warn when giving eye medicine - ANSWERblurred vision
how to administer inhaler - ANSWERshake before you puff, wait 2 mins, before each
puff of same med/ inhaler, wait 5 mins if diff med/inhaler
why do you need to rinse your mouth out after using inhaler - ANSWERto avoid thrush a
how to administer ear drops for kids under 3 - ANSWERpull down and back "kids are
short" leave head in position for 3-5 mins
how to administer ear drops for kids over 3 and up - ANSWERpull up and back leave
head in position for 3-5 mins
administering nose drops do what - ANSWERtilt head back
administering nose sprays do what - ANSWERsit upright / high flowers
interventions for nose drops and sprays - ANSWERhave pt blow their nose prior
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