biosafety & Biosecurity Questions and
Answers
BMBL
✓ ~~~ Biosafety in Microbiological and Biomedical Laboratories
✓ a set of guidelines for the safe handling and containment of biological agents
✓ -established by the CDC and NIH
Biological Agents
✓ ~~~ Infectious microorganisms and potentially hazardous biological materials
Risk Assessment
✓ ~~~ process that enables the appropriate selection of microbiological practices, safety
equipment, and facility safeguards that can prevent laboratory-associated infections
(LAIs)
LAI
✓ ~~~ Laboratory-Associated Infections
How has the rate of Laboratory-Associated Infections decreased?
✓ ~~~ Improvements in containment equipment, engineering controls, and a greater
emphasis on safety training
What are the primary risk criteria
✓ ~~~ • Infectivity
• Severity of disease
• Transmissibility
• Nature of the work being conducted
, • Agent origin - for agents that cause moderate to severe disease
What are common ways of developing LAIs?
✓ ~~~ exposure to contaminated aerosols and droplets
Biological Risk Assessment
✓ ~~~ • Staff's training and technical experience
• Activities that might lead to staff exposure
• Probability that agent exposure will lead to a LAI
• Availability of preventive measures and effective treatments for the disease
• Consequences of an infection
How are infectious agents classified by NIH?
✓ ~~~ into ascending risk groups from 1-4
-higher # indicates higher risk of hazardous characteristics that may cause human
disease
How are infectious agents classified by WHO?
✓ ~~~ based on degree of Dz hazard to humans and animals, natural route of the Dz's
transmission, preventative measures, and effective treatments
WHO
✓ ~~~ World Health Organization
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