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Exam (elaborations)

NR 566 WEEK #1 STUDY GUIDE EXAM QUESTIONS AND ANSWERS

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NR 566 WEEK #1 STUDY GUIDE EXAM QUESTIONS AND ANSWERS

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  • August 15, 2024
  • 10
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR566
  • NR566
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biggdreamer
NR 566 WEEK #1 STUDY GUIDE EXAM
QUESTIONS AND ANSWERS
What are the major antibiotic drug classes - Answer-Beta-lactams: penicillins
Beta-lactams: Cephalosporins
fluoroquinolones
tetracyclines and macrolides
sulfonamides, trimethoprim, &nitrofurantoin

What is the primary goal of antibiotic therapy - Answer-kill bacteria without harming host
tissue

Bactericidal antibiotics - Answer-directly kill bacteria

bacteriostatic antibiotics - Answer-Antibiotics that do not actually kill bacteria but rather
inhibit bacterial proliferation while the hosts immune system does the killing

which antibiotics are preferred for immunocompromised patients: bactericidal or
bacteriostatic - Answer-bactericidal

which antibiotics are preferred for patients with an overwhelming infection: bactericidal
or bacteriostatic - Answer-bactericidal

broad spectrum antibiotics - Answer-affect a broad range of gram-positive or gram-
negative bacteria

narrow spectrum antibiotics - Answer-Effective against specific bacteria

which is used for empiric therapy: narrow or broad - Answer-broad spectrum

Risks of Broad Spectrum - Answer-disruption of normal floral
increases risk of development of antibiotic resistance

which antibiotics increase the risk of antibiotic resistance: narrow or broad spectrum and
why - Answer-Broad spectrum because they kill more competing organisms than narrow
spectrum drugs

is narrow or broad spectrum antibiotics preferred - Answer-narrow is preferred when
possible.

broad spectrum only used when pathogen is unknown or when multiple types of
bacteria is suspected

Bactericidal drugs - Answer-Aminoglycosides

, Beta-lactams
fluoroquinolones
Metronidazole
Vancomycin
streptogramins
most antimycobacterial agents (rifampin, isoniazid, streptomycin, etc)

bacteriostatic drugs - Answer-clindamycin
macrolides
sulfonamides
tetracyclines

When is empiric therapy used? - Answer-when treatment is started without cultures or
when culture results are not back yet

who needs empiric therapy - Answer-critically ill pts after first set of cxs
hospitalized pts until css are available
ambulatory pts based on clinical presentation

Penicillins MOA - Answer-inhibit cell wall synthesis; bactericidal

penicillins primarily excreted how - Answer-in urine

what needs to be monitored when giving penicillins - Answer-renal function

what happens if renal insufficiency occurs while giving penicillins - Answer-prolonged
half-life leading to toxicity

Penicillin distribution - Answer--Well distributed to most body tissues
-Penetration to CSF and eye tissues poor in absence of inflammation

narrow-spectrum penicillinase sensitive drugs - Answer-penicillin G
penicillin V

narrow-spectrum penicillinase sensitive susceptible pathogens - Answer-streptococci,
Neisseria, anaerobes

narrow-spectrum penicillinase resistant drugs - Answer-naficillin
oxacillin
dicloxacillin

narrow-spectrum penicillinase resistant susceptible pathogens - Answer-S. Aureus
streptococci

Broad-spectrum penicillins - Answer-Ampicillin
Amoxicillin

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